Disorders - Binge Eating Disorders
Vidmar, Alaina P., Salvy, Sarah J., Wee, Choo Phei, Pretlow, Robert, Fox, D., Yee, Jennifer K., Garell, Cambria, Glasner, Suzette, Mittelman, Steven D.
Objective: This randomized clinical trial tested the effectiveness of an addictionbased
digital weight-loss intervention, focusing on withdrawal/abstinence from selfidentified problem foods, snacking and excessive amounts at meals, and
discomfort displacement, with and without coaching, compared to an in-person, multi-disciplinary, care model among adolescents with obesity. We
hypothesized that the digital intervention with coaching would yield greater weight loss and lower delivery burden than the standard clinical arm,
and greater participant engagement than the digital arm without coaching.\rMethods: Adolescents were randomized to app intervention, with or without
coaching, or in-person multidisciplinary obesity intervention for 6 months. The primary outcome was change in %BMIp95 at weeks 12 and 24. A mixed-
effects linear regression model was used to assess the association between change in %BMIp95 and intervention arm. We were also interested in
assessing delivery burden, participant engagement and evaluating the relationships between weight change and demographic characteristics, mood,
executive function and eating behaviours.\rResults: All adolescents (n = 161; BMI
Pediatric Obesity Vol 18(3), 2023, ArtID e12990, 18(3) :
- Year: 2023
- Problem: Eating Disorders
(any), Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Technology, interventions delivered using technology (e.g. online, SMS)
Schneider, E., Martin, E., Rotshtein, P., Qureshi, K. L., Chamberlain, S. R., Spetter, M. S., Dourish, C. T., Higgs, S.
Lisdexamfetamine dimesylate (LDX) is the only drug currently approved by the FDA for the treatment of Binge-
Eating Disorder (BED), but little is known about the behavioural mechanisms that underpin the efficacy of LDX in treating BED. We examined the
behavioural and neural effects of an acute dose of LDX (50 mg) in 22 women with binge-eating symptomatology using a randomised, crossover, double-
blind, placebo-controlled experimental medicine design. LDX reduced self-reported appetite ratings and intake of both a pasta meal and a palatable
cookie snack. LDX also decreased the eating rate of pasta but not of cookies and reduced self-reported liking ratings for pasta at the end of the
meal. When viewing food pictures during an fMRI scan, LDX reduced activity bilaterally in the thalamus. LDX enhanced sustained attention and reduced
impulsive responding in a continuous performance task but had no effect on emotional bias or working memory. These results suggest the observed
effects of LDX on food intake (and by implication the efficacy of LDX in treating BED) may be related to the actions of the drug to enhance satiety,
reduce food-related reward responding when full and/or increase cognitive control. Novel pharmacotherapies for BED might be most effective if they
have a broad spectrum of effects on appetite, reward and cognition. Copyright © 2021, The Author(s).
Translational Psychiatry, 12(1) (no pagination) :
- Year: 2022
- Problem: Eating Disorders
(any), Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Biological Interventions
(any), Appetite
moderators, Other biological interventions
Das, R. K., Cawley, E.
A., Simeonov, L., Piazza, G., Schmidt, U., Wiers, R. W. H.
J., Kamboj, S. K.
Binge eating is
increasingly prevalent among adolescents and young adults and can have a lasting harmful impact on mental and physical health. Mechanistic insights
suggest that aberrant reward-learning and biased cognitive processing may be involved in the aetiology of binge eating. We therefore investigated
whether recently developed approaches to catalyse brief interventions by putatively updating maladaptive memory could also boost the effects of
cognitive bias modification training on binge eating behaviour. A non-treatment-seeking sample of 90 binge eating young adults were evenly randomised
to undergo either selective food response inhibition training, or sham training following binge memory reactivation. A third group received training
without binge memory reactivation. Laboratory measures of reactivity and biased responses to food cues were assessed pre-post intervention and
bingeing behaviour and disordered eating assessed up to 9 months post-intervention. The protocol was pre-registered at https://osf.io/82c4r/ . We
found limited evidence of premorbid biased processing in lab-assessed measures of cognitive biases to self-selected images of typical binge foods.
Accordingly, there was little evidence of CBM reducing these biases and this was not boosted by prior 'reactivation' of binge food reward memories.
No group differences were observed on long-term bingeing behaviour, caloric consumption or disordered eating symptomatology. These findings align
with recent studies showing limited impact of selective inhibition training on binge eating and do not permit conclusions regarding the utility of
retrieval-dependent memory 'update' mechanisms as a treatment catalyst for response inhibition training. Copyright © 2022. The Author(s).
Scientific
reports, 12(1) : 9281
- Year: 2022
- Problem: Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Attention/cognitive bias
modification
D'Adamo, L., Monterubio, G., Claire, A., Balantekin, K., Taylor, C., Fitzsimmons-Craft, E., Wilfley, D.
Background: Binge-type eating disorders (EDs; i.e., bulimia nervosa and binge eating disorder) are common among young adults with
overweight/ obesity, yet few interventions target both conditions. We tested an online guided self-help intervention that provided cognitive
behavioral therapy (CBT)-based tools for EDs and multicomponent behavioral weight loss (BWL) strategies to young adults with binge-type EDs and
overweight/obesity. Program engagement and change in weight and ED symptoms from baseline to post-intervention were compared between the combined
intervention (CBT+BWL) and an ED-only intervention. Method(s): 60 young adults with clinical/subclinical binge-type EDs and overweight/obesity (BMI M
= 34.4+/-7.4; global ED psychopathology M = 3.7+/-0.9, range = 0-6; binge episode frequency M over the last 28 days = 11.1+/-9.3) were randomized to
CBT+BWL or an EDonly condition. Participants received self-help session content for 8 weeks and self-reported ED symptoms and weight at baseline, 4-
weeks, and post-intervention (8-weeks). Linear mixed models, negative binomial models, Chi-squared tests, and t-tests compared changes in global ED
psychopathology, binge episode frequency, program completion, and session engagement. Result(s): No differences in weight change, ED symptom change,
program completion, or session engagement emerged between the conditions. Both groups achieved significant reductions in ED psychopathology (by 1.3
points in CBT+BWL and 1.4 points in EDonly) and binge frequency (by 4.9 episodes in CBT+BWL and 7.7 episodes in ED-only) from baseline to 8-weeks
(ps<.01). Neither condition achieved significant reductions in weight. 47% of participants completed all 8 sessions. Conclusion(s): CBT+BWL produced
similar improvements in ED symptoms versus CBT alone, suggesting that adding BWL content did not increase risk for EDs. Research should explore BWL
components that may promote weight change in young adults and evaluate their influence on ED risk, as well as for whom a CBT+BWL intervention may
impact ED risk.
Obesity, 30(Supplement
1) : 152
- Year: 2022
- Problem: Eating Disorders
(any), Binge Eating Disorders, Bulimia Nervosa
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Other Psychological Interventions
Tanis, J., Vroling, M. S., Martijn, C., van-Heijningen, L. A. Maas, J., Keijsers, G. P. J.
Binge eating disorder (BED) and bulimia nervosa (BN) are characterized by binge eating. Frequently related
to negative affect, binge eating is considered unwanted eating behavior. It is often preceded by a shift away from the goal of a healthy eating
pattern. Implementation intentions are 'if-then' plans that may prevent such shifts in goals. In a students' sample with subthreshold binge
eating, two implementation intention conditions were compared to a control condition in which only goals were formed. In the behavior-focused
condition, implementation intentions targeted binge eating; in the emotion-focused condition, implementation intentions targeted negative affect
preceding binge eating. All participants received three sessions and kept food diaries for four weeks, followed by a post-test and a one-month,
three-months, and six-months follow-up. Compared to the control condition, both implementation intention conditions showed significant and large
reductions in binge eating lasting for six months. Effects did not differ between both implementation intention conditions. Three implementation
intention sessions reduced subthreshold binge eating. This continued for six months after the final session. Contrary to expectations, behavior-
focused and emotion-focused implementation intentions were equally effective, possibly due to other triggers than negative affect. Future research
should address their usefulness in BED and BN. Copyright © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.
Eating Disorders., :
- Year: 2021
- Problem: Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Maglia,
M., Corello, G., Caponnetto, P.
According to the WHO definition,
\"telemedicine is the provision of health services, where distance is a critical factor, by all health professionals who use information and
communication technologies for the exchange of valid information for the diagnosis, treatment and prevention of diseases, research and evaluation,
and for the continuous training of health professionals, all in the interest of advancing the health of individuals and their communities\". The
purpose of our review work is specifically to investigate the effects of telemedicine in the treatment and prevention of eating disorders in
adolescents. From June 2021 to (September 2021) in the databases of the Web of Science, EMBASE, PsycINFO and CINHAL, using search terms such as
telehealth, eating disorder, adolescents, Internet/online treatments CBT and FB-T, anorexia nervosa, bulimia nervosa and binge eating disorder. The
articles resulting from the search phases in the databases listed above produced a total of 176 items. Once the procedures for selecting the works
were completed, only four studies were included in the review. Modern e-health psychological approaches in the treatment of eating disorders provide
potential bases of continuous assistance that are decidedly less burdensome in the costs of territorial services in the case that they are not
identified as necessary. Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
International Journal of Environmental Research and Public Health, 18(23) (no
pagination) :
- Year: 2021
- Problem: Eating Disorders
(any), Anorexia Nervosa, Binge Eating Disorders, Bulimia Nervosa
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any)
Kwag, K. H., Lee, Y. K., Lee, H. R., Kim, Y. R.
Purpose: The aim of this study was to evaluate the feasibility, acceptability, and effectiveness of an internet-based
guided self-help intervention for female college students with bulimia nervosa (BN) or binge eating disorder (BED). Material(s) and Method(s): A
total of 19 female college students with either BN or BED participated in the study. We assessed eating psychopathology and affective symptoms at
baseline, post-intervention, and 1-month follow-up. Result(s): Our results demonstrated that the participants in the intervention showed the
reduction of eating psychopathology and affective symptoms at post-intervention and the reduced conditions were maintained at 1-month follow-up. The
participants in the intervention showed lowered eating psychopathology (binge/overeating and types of compensatory behaviors) compared to those in
the control group. Conclusion(s): The internet-based intervention program is feasible, acceptable, and effective for improving eating psychopathology
and affective symptoms in young adult women with bulimic-type eating disorders.
, 13(SUPPL 1) :
- Year: 2021
- Problem: Binge Eating Disorders, Bulimia Nervosa
- Type: Controlled clinical trials
-
Stage: Disorder established (diagnosed disorder), At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Self-help, Technology, interventions delivered using technology (e.g. online, SMS)
Yang, J., Han, K. S.
Background: Binge
eating behavior is highly likely to progress to an eating disorder, with female students\rparticularly at risk.\rObjective: This study aimed to
verify the effect of a binge eating behavior management program, based on\rrational emotive behavior therapy (REBT), on binge eating behavior and
related cognitive and emotional factors\ramong female college students.\rMethod: The study, conducted from November 1 to December 2, 2016, involved a
pretest-posttest design and\rnonequivalent control group. The sample included 24 and 22 first- to third-year students, from a college in South
\rKorea, in the experimental and control groups, respectively. Data were collected using self-esteem, covert\rnarcissism, perfectionism, body
dissatisfaction, anxiety, depression, and binge eating scales and analyzed via\rfrequency analysis,
Journal of Eating
Disorders, 8 : ArtID 65
- Year: 2020
- Problem: Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Leslie, M., Leppanen, J., Paloyelis, Y., Treasure, J.
The current study aimed to test the influence of oxytocin on palatable food intake, 24-h caloric consumption, and stress
in women with bulimia nervosa and binge eating disorder. We recruited 25 women with DSM-5 bulimia nervosa or binge eating disorder, and 27 weight-
matched comparison women without history of an eating disorder. We employed a double-blind, placebo-controlled crossover design in which each
participant attended the lab for two experimental sessions, receiving a divided dose of 64IU intranasal oxytocin in one session and equivalent volume
of placebo nasal spray in the opposite session. The order of administration was pseudo-randomised across participants. We hypothesised that a divided
dose of 64IU intranasal oxytocin administration would reduce subjective hunger, the immediate consumption of palatable food, 24-h calorie
consumption, and the incidence of binge eating when compared to placebo. We also hypothesised that oxytocin administration would be associated with
lower levels of stress and salivary cortisol, and that there would be an interaction with participant group such that oxytocin would reduce eating
behaviour and stress to a greater degree in women with bulimia nervosa or binge eating disorder, compared to women without history of an eating
disorder. We did not find a significant effect of oxytocin on any of the measurements of eating behaviour, subjective stress, or salivary cortisol.
We recommend that future studies test the dose-response effect of oxytocin on eating behaviours and stress in human populations with eating disorders
to further clarify the moderating factors for oxytocin's effect on eating. Copyright © 2018 Elsevier B.V.
Molecular and Cellular
Endocrinology., :
- Year: 2018
- Problem: Binge Eating Disorders, Bulimia Nervosa
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Biological Interventions
(any), Other biological interventions
Leslie, M., Leppanen, J., Paloyelis, Y., Treasure, J.
The current study aimed to test the influence of oxytocin on palatable food intake, 24-h caloric consumption, and stress
in women with bulimia nervosa and binge eating disorder. We recruited 25 women with DSM-5 bulimia nervosa or binge eating disorder, and 27 weight-
matched comparison women without history of an eating disorder. We employed a double-blind, placebo-controlled crossover design in which each
participant attended the lab for two experimental sessions, receiving a divided dose of 64IU intranasal oxytocin in one session and equivalent volume
of placebo nasal spray in the opposite session. The order of administration was pseudo-randomised across participants. We hypothesised that a divided
dose of 64IU intranasal oxytocin administration would reduce subjective hunger, the immediate consumption of palatable food, 24-h calorie
consumption, and the incidence of binge eating when compared to placebo. We also hypothesised that oxytocin administration would be associated with
lower levels of stress and salivary cortisol, and that there would be an interaction with participant group such that oxytocin would reduce eating
behaviour and stress to a greater degree in women with bulimia nervosa or binge eating disorder, compared to women without history of an eating
disorder. We did not find a significant effect of oxytocin on any of the measurements of eating behaviour, subjective stress, or salivary cortisol.
We recommend that future studies test the dose-response effect of oxytocin on eating behaviours and stress in human populations with eating disorders
to further clarify the moderating factors for oxytocin's effect on eating. Copyright © 2018 Elsevier B.V.
Molecular and Cellular
Endocrinology., :
- Year: 2018
- Problem: Binge Eating Disorders, Bulimia Nervosa
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Biological Interventions
(any), Other biological interventions
Schyns, G., Roefs, A., Smulders, F. T., Jansen, A.
Background and objectives: This study tested whether two
sessions of food cue exposure therapy reduced eating in the absence of hunger (EAH), specified for exposed and non-exposed food, in overweight and
obese adolescents, and whether habituation of food cue reactivity and reduced CS-US expectancies predicted a decrease in EAH. Methods: 41 overweight
adolescents (aged 12-18 years) were randomly assigned to a cue exposure intervention or a lifestyle intervention (control condition). Habituation of
food cue reactivity (self-reported desire to eat and salivation) and CS-US expectancy were measured during both sessions, and EAH was measured at the
end of session two. Results: Compared to the control condition, the cue exposure condition showed less EAH for the exposed food item as well as for
the non-exposed food items. Larger within-session (WSH) and between-session habituation (BSH) of cue reactivity were not related to less EAH, change
in CS-US expectancy was unrelated to EAH. Limitations: The study was underpowered, and compliance to homework instructions between sessions was poor,
intervention effects might have been larger when participants adhered to daily homework exercises. Conclusions: Food cue exposure was effective to
reduce EAH of exposed and non-exposed food items, indicating generalisability of the exposure effect. In line with exposure effects in anxiety
disorders, habituation was not found to benefit outcome, though the present data do also not provide evidence that CS-US expectancy violation
predicts EAH. (PsycINFO Database Record (c) 2017 APA, all rights reserved)
Journal of Behavior Therapy and Experimental Psychiatry, 58 : 68-
77
- Year: 2018
- Problem: Binge Eating Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Psychoeducation, Other Psychological Interventions
Marzilli, E., Cerniglia, L., Cimino, S.
Binge eating disorder (BED) represents one of the most problematic clinical conditions among youths. Research has shown that the
developmental stage of adolescence is a critical stage for the onset of eating disorders (EDs), with a peak prevalence of BED at the age of 16-17
years. Several studies among adults with BED have underlined that it is associated with a broad spectrum of negative consequences, including higher
concern about shape and weight, difficulties in social functioning, and emotional-behavioral problems. This review aimed to examine studies focused
on the prevalence of BED in the adolescent population, its impact in terms of physical, social, and psychological outcomes, and possible strategies
of psychological intervention. The review of international literature was made on paper material and electronic databases ProQuest, PsycArticles, and
PsycInfo, and the Scopus index were used to verify the scientific relevance of the papers. Epidemiological research that examined the prevalence of
BED in adolescent samples in accordance with Diagnostic and Statistical Manual of Mental Disorders, 4th Edition showed a prevalence ranging from 1%
to 4%. More recently, only a few studies have investigated the prevalence of BED, in accordance with the Diagnostic and Statistical Manual of
Disorders, Fifth Edition criteria, reporting a prevalence of ~1%-5%. Studies that focused on the possible impact that BED may have on physical,
psychological, and social functioning showed that adolescents with BED have an increased risk of developing various adverse consequences, including
obesity, social problems, substance use, suicidality, and other psychological difficulties, especially in the internalizing area. Despite the
evidence, to date, reviews on possible and effective psychological treatment for BED among young population are rare and focused primarily on
adolescent females. Copyright © 2018 Marzilli et al.
Adolescent Health, Medicine and Therapeutics, 9 : 17-
30
- Year: 2018
- Problem: Binge Eating Disorders
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Dialectical behavioural therapy
(DBT), Interpersonal therapy (IPT), Psychoeducation