Disorders - depressive disorders
Vivas-Fernandez, M., Garcia-Lopez, L. J., Piqueras, J. A., Muela-Martinez,
J. A., Canals-Sans, J., Espinosa-Fernandez, L., Jimenez-Vazquez, D., Diaz-Castela, M. D. M., Morales-Hidalgo, P., Rivera, M., Ehrenreich-May, J.
Significant evidence does exist
on the effectiveness of transdiagnostic interventions to improve emotional problems in clinical populations, and their application as universal and
indicated prevention programs. However, no randomized controlled trials (RCT) studying selective transdiagnostic prevention intervention have been
published. This is the first known RCT to evaluate the efficacy/effectiveness of an evidence-based selective prevention transdiagnostic program for
emotional problems in adolescents. The impact of three different interventions was evaluated: (1) PROCARE (Preventive transdiagnostic intervention
for Adolescents at Risk for Emotional disorders), which is a group-based, abbreviated version of the Unified Protocol for Transdiagnostic Treatment
of Emotional Disorders in Adolescents (UP-A), along with adding a booster session to reduce risk of onset of anxiety and depression, (2) PROCARE + ,
which includes the PROCARE protocol along with personalized add-on modules tailored to match adolescents' risk factors, and (3) an active control
condition (ACC) based on emotional psychoeducation. In total, 208 adolescents (48.5% girls) evidencing high risk and low protective factors were
randomized and allocated to PROCARE, PROCARE + or ACC. Data from 153 adolescents who completed all assessments in the different phases of the study
were analyzed. Self- and parent-reported measures were taken at baseline, as well as after the intervention, a 6 month follow-up was carried out,
together with a 1 month follow-up after the booster session. Differences between conditions were significant on most of the outcome measures, with
superior effect sizes for PROCARE + in the short and long term. Interventions were acceptable in terms of acceptability, with good satisfaction
rates. Tailored targeted selective transdiagnostic interventions focused on mitigating risk factors and promoting protective factors in vulnerable
adolescents are promising.
Child & Adolescent Psychiatry & Mental Health
[Electronic Resource], 17(1) : 77
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Victor-Aigbodion, V., Eseadi, C., Ardi, Z., Sewagegn, A. A., Ololo, K., Abonor, L. B., Aloh, H. E., Falade, T. A., Effanga, O. A.
BACKGROUND: Studies reporting the incidence of depression among medical
students have been on the increase. This research sought to determine whether rational emotive behavior therapy (REBT) can be applied to help manage
depression in Nigerian undergraduate medical students.\rMETHODS: A randomized pretest/posttest control group design was used in this study. Ninety
medical students with depression participated in the study and were assisted using the REBT depression manual. Using a mixed-model repeated measures
analysis of variance, the researchers examined the intervention data.\rRESULTS: The depressive symptoms and its associated irrational beliefs among
medical students in the treatment arm were significantly altered by REBT intervention at posttest and this positive outcome was sustained at follow-
up in contrast to the control arm.\rCONCLUSION: REBT intervention significantly improves medical students' ability to overcome depression and
irrational beliefs. Similar studies could be conducted in a variety of academic settings where these students can be found to expand the findings of
this study.
, 102(4) : e32724
- Year: 2023
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Venturo-Conerly, K. E., Eisenman,
D., Wasil, A. R., Singla, D. R., Weisz, J. R.
OBJECTIVE: Because most youth psychotherapies are
developed and tested in high-income countries, relatively little is known about their effectiveness or moderators in low- and middle-income countries
(LMICs). To address this gap, we conducted a meta-analysis of randomized controlled trials (RCTs) testing psychotherapies for youth with multiple
psychiatric conditions in LMICs, and we tested candidate moderators.\rMETHOD: We searched 9 international databases for RCTs of youth psychotherapies
in LMICs published through January 2021. The RCTs targeted elevated symptoms of youth anxiety (including posttraumatic stress disorder [PTSD] and
obsessive-compulsive disorder), depression, conduct problems, and attention problems. Using robust variance estimation, we estimated the pooled
effect sizes (Hedges g) at posttreatment and follow-up for intervention vs control conditions.\rRESULTS: Of 5,145 articles identified, 34 articles
(with 43 treatment-control comparisons and 4,176 participants) met methodological standards and were included. The overall pooled g with winsorized
outliers was 1.01 (95% CI = 0.72-1.29, p < .001) at posttreatment and 0.68 (95% CI = 0.29-1.07, p = .003) at follow-up. Interventions delivered by
professional clinicians significantly outperformed those delivered by lay providers (g = 1.59 vs 0.53), but all interventions for conduct problems
were delivered by professionals, and the difference for interventions targeting internalizing problems (g = 1.33 vs .53) was not significant.
Interventions developed non-locally were more effective if they were not adapted to local contexts than if they were adapted locally (g = 2.31 vs
0.66), highlighting a need for further research on effective adaptations. Significant risk of bias was identified.\rCONCLUSION: Overall, pooled
effects of youth psychotherapies in LMICs were markedly larger than those in recent comparable non-LMIC meta-analyses, which have shown small-to-
medium effects for youth psychotherapies. Findings highlight the potential benefits of youth psychotherapies in LMICs, as well as a need for more
RCTs and improved study quality.\rSTUDY PREREGISTRATION INFORMATION: Effectiveness of Youth Psychotherapy Interventions in Low- and Middle-Income
Countries (LMICs): A Systematic Review and Meta-Analysis of Randomized Clinical Trials; https://www.crd.york.ac.uk/PROSPERO/; CRD42021240031.
Journal of the American Academy of Child & Adolescent Psychiatry, 62(8) : 859-
873
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any)
Uebelacker, L. A., Wolff, J. C., Guo, J., Conte, K., Tremont, G., Kraines, M., O'Keeffe, B., Fristad, M. A., Yen, S.
PURPOSE: Given increasing
rates of depression in adolescents, there is a clear need for innovative treatments. In this pilot randomized clinical trial, we assessed
acceptability and feasibility of two group-based interventions: yoga and cognitive-behavioral therapy (CBT). The goal of this work is to prepare for
a future fully powered randomized trial to test the hypothesis that yoga is not inferior to an established adolescent depression treatment, namely,
group CBT. METHOD(S): We enrolled 42 adolescents with elevated depression symptoms. Participants were randomly assigned to a 12-week group-based
intervention, yoga or CBT. We had a priori feasibility and acceptability targets, including for recruitment rate, retention rate, expectancy,
credibility, program satisfaction, class attendance, engagement in home practice, and instructor/leader manual adherence. We assessed adverse events,
and within-subject changes in outcomes (depression, anxiety, impairment, sleep disturbance) and possible mediators (mindfulness, self-compassion).
RESULT(S): Both interventions met most acceptability and feasibility targets. The only target not met related to low engagement in home practice.
Participants within each study arm showed decreased depression symptoms over time and increased self-compassion. CONCLUSION(S): A yoga intervention
appears to be acceptable and feasible to adolescents with depression. However, it may be challenging for this group to engage in unstructured home
practice.
Clinical child psychology and psychiatry, 28(2) : 525-
540
- Year: 2023
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention), Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Mind-body exercises (e.g. yoga, tai chi, qigong)
Turan, N., Canbulat, S.
PURPOSE: This
study aimed to examine the effectiveness of the training program which was based on cognitive behavioral theory on accepting and expressing emotions
in terms of nurses' psychological resilience and depression levels.\rDESIGN AND METHODS: The study is an intervention study with a control group
conducted with pretest, posttest, and two-year follow-up test design in line with Consolidated Standards of Reporting Trials (CONSORT). The
participants in the intervention group attended an eight-week accepting and expressing emotions training program, while those in the control group
did not. The Psychological Resilience Scale for Adults (RSA) and Beck's Depression Inventory (BDI) were applied to both groups as pre-test, post-
test and 6-month follow-up (T2), 12-month follow-up (T3) and 24-month follow-up (T4).\rRESULTS: It was determined that there was a significant change
in RSA scale scores of the intervention group, and that the effect of group * time interaction for all scores was significant. An increase in the
total score was found for all follow-up periods with respect to T1. A significant decrease was determined in BDI scores of the intervention group,
and the effect of group-time interaction for all scores was found to be significant. It was found that there was a decrease in the scores of the
intervention group in all follow-up periods with respect to T1.\rCONCLUSIONS: The results obtained from the study showed that the training program
conducted with groups on accepting and expressing emotions was effective on the nurses' psychological resilience and depression scores.\rPRACTICE
IMPLICATIONS: Training programs that develop the skills of accepting and expression emotions can help nurses find their thoughts underlying their
emotions. Thus, depression levels of nurses can decrease, and their psychological resilience can improve. This situation can help in terms of
reducing workplace stress of nurses and can cause their working life to be more effective.
, 44 : 1-7
- Year: 2023
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Thomas, E. B. K., Sagorac Gruichich, T., Maronge, J. M., Hoel, S., Victory, A., Stowe, Z. N., Cochran, A.
BACKGROUND: Extant gaps in mental health services are intensified among first-generation college students.
Improving access to empirically based interventions is critical, and mobile health (mHealth) interventions are growing in support. Acceptance and
commitment therapy (ACT) is an empirically supported intervention that has been applied to college students, via mobile app, and in brief intervals.
\rOBJECTIVE: This study evaluated the safety, feasibility, and effectiveness of an ACT-based mHealth intervention using a microrandomized trial (MRT)
design.\rMETHODS: Participants (N=34) were 18- to 19-year-old first-generation college students reporting distress, who participated in a 6-week
intervention period of twice-daily assessments and randomization to intervention. Participants logged symptoms, moods, and behaviors on the mobile
app Lorevimo. After the assessment, participants were randomized to an ACT-based intervention or no intervention. Analyses examined proximal change
after randomization using a weighted and centered least squares approach. Outcomes included values-based and avoidance behavior, as well as
depressive symptoms and perceived stress.\rRESULTS: The findings indicated the intervention was safe and feasible. The intervention increased
values-based behavior but did not decrease avoidance behavior. The intervention reduced depressive symptoms but not perceived stress.\rCONCLUSIONS:
An MRT of an mHealth ACT-based intervention among distressed first-generation college students suggests that a larger MRT is warranted. Future
investigations may tailor interventions to contexts where intervention is most impactful.\rTRIAL REGISTRATION: ClinicalTrials.gov NCT04081662;
https://clinicaltrials.gov/show/NCT04081662.\rInternational registered report identifier (irrid): Rr2-10.2196/17086.
JMIR Mental Health, 10 : e43065
- Year: 2023
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Acceptance & commitment therapy
(ACT), Technology, interventions delivered using technology (e.g. online, SMS)
Thielemann, J. F. B., Kasparik, B., Konig,
J., Unterhitzenberger, J., Rosner, R.
The efficacy of trauma-focused treatments for children and adolescents is well researched. However, less is known about the long-term
and caregiver-reported effects. Searched databases were PsychInfo, MEDLINE, Cochrane Library, PTSDPubs, PubMed, Web of Science, and OpenGrey.
Treatment effects of trauma-focused cognitive behavioral therapy (TF-CBT) were computed at 12-month follow-up with posttraumatic stress symptoms
(PTSS) as primary outcome and symptoms of depression, anxiety, and grief as secondary outcomes. Concordance between participant and caregiver ratings
were investigated. TF-CBT showed large improvements across all outcomes from pre-treatment to 12-month follow-up (PTSS: g = 1.71, CI 1.27-2.15) and
favorable results compared to active treatments and treatment as usual at 12-month follow-up (PTSS: g = .35, CI .13-.56). More pronounced effects
were found in group settings. No significant differences were detected between participant and caregiver ratings with high reliability across almost
all outcomes and assessment points. TF-CBT is a reliable treatment for pediatric PTSS and secondary symptoms with stable results at 12-month follow-
up.
Child maltreatment, : 10775595231167383
- Year: 2023
- Problem: Anxiety Disorders (any), Post Traumatic Stress Disorder, Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Trauma-focused cognitive behavioural therapy (TF-
CBT)
Tating, D. L. R. P., Tamayo, R. L. J., Melendres, J. C. N., Chin, I. K., Gilo, E. L. C., Nassereddine, G.
BACKGROUND: Nursing students experience higher stress and burnout compared to students in other health professions, with a prevalence
rate of as high as 20%. More recently, they have been affected by changes in nursing education due to the COVID-19 pandemic, such as requirements for
social isolation and distance learning. Although there are existing studies on interventions that address academic burnout among nursing students,
there is no synthesis of randomized trials on this topic. AIM: This study aimed to systematically synthesize studies of interventions for academic
burnout among nursing students. METHOD(S): A systematic search for randomized controlled trials was performed in PubMed, CINAHL, CENTRAL, Web of
Science, and Scopus. Eligibility criteria were based on study directness in relation to the Patient, Intervention, Comparison, and Outcome (PICO)
question. Two review authors independently screened articles for inclusion, collected data from the included studies, and performed risk of bias
assessments using the Cochrane Risk of Bias Tool 2.0. A narrative synthesis was performed. This review was registered a priori in PROSPERO
(CRD42022350196). RESULT(S): Six papers were included in this review. Various interventions were studied: Qigong exercises, progressive muscle
relaxation, autogenic therapy and laughter therapy, didactic behavioral sessions focusing on personal and professional development, and coping skills
enhancement. The effects of these interventions on academic burnout, depression, and stress among nursing students were short term and their benefits
over time remain uncertain. LINKING EVIDENCE TO ACTION: Progressive muscle relaxation and cognitive behavioral interventions demonstrated short-term
positive effects on academic burnout, depression, and stress among nursing students. These findings may support the development of individual-level
and organizational-level initiatives for nursing students aimed to lessen or prevent academic burnout. Large-scale, high-quality studies on the
effect of interventions on academic burden in various settings and cultures are needed. Copyright © 2023 Sigma Theta Tau International.
Worldviews on
Evidence-Based Bursing, 20(2) : 153-161
- Year: 2023
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Psychological Interventions
(any)
Tan, J.
Background. With the increasing social employment pressure, the psychological pressure of college students in their daily
study and life is also increasing. Because students' physical and mental growth is not sound, it is difficult for them to carry out targeted self-
intervention and adjustment against psychological pressure, which leads to long-term accumulation of negative psychology and eventually forms
depressive symptoms. In recent years, the number of depression patients in colleges and universities has been increasing. It is necessary to form a
daily treatment strategy system that is in line with students' psychological characteristics. Subjects and Methods. 90 students diagnosed with
depression were selected and divided into three groups. The first group was a single drug intervention group, which only used the common form of
depression drug intervention. The second group was a single art design appreciation intervention, which used professional art design and appreciation
psychological intervention strategies to intervene students' depression. The third group is the design appreciation and drug combined intervention
group. The students in this group participated in professional art design and appreciation psychological intervention while taking antidepressant
drug treatment. The study collected the depression psychological status of the three groups of patients before and after treatment, and used the
collected data for quantitative analysis. Results. The research results showed that before the start of treatment, the Self-Rating Depression (SDS)
scores of the three groups of students with depression were 63.21 points in the single drug intervention group, 64.32 points in the single art design
appreciation intervention group and 63.54 points in the art design appreciation and drug combined intervention group. It showed that the levels of
depression symptoms of the three groups of students before the intervention were similar. After intervention, the SDS score of the single drug
intervention group decreased to 45.22 points, the SDS score of the single art design appreciation intervention group decreased to 46.51 points, and
the SDS score of art design appreciation and drug combined intervention decreased to 40.13 points. It can be seen that the intervention effect of art
design appreciation and drug intervention is the most obvious. Compared with the other two methods, this method is more conducive to the depression
intervention for students. Conclusions. From the comparison of the patients' condition in the single drug intervention group, the single art design
appreciation intervention group, and the art design appreciation and drug combination intervention group before and after the intervention, it can be
seen that the art design appreciation and drug combination intervention strategy designed by the research is more conducive to forming a better
intervention effect in the student group, helping them to establish a psychological reaction mechanism in life with antidepressant drugs and reduce
the severity of self-depression.
CNS Spectrums, 28(Supplement
1) : S10
- Year: 2023
- Problem: Depressive Disorders
- Type: Controlled clinical trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Biological Interventions
(any), Antidepressants
(any), Complementary & Alternative
Interventions (CAM), Creative expression: music, dance, drama, art
Szota,
K., Schulte, K. L., Christiansen, H.
Although
treatment guidelines recommend interventions entailing caregiver involvement for children and adolescents following traumatic experiences, evidence
on their effectiveness is inconsistent. The present systematic review and meta-analysis considered possible moderators of their effectiveness.
METHOD(S): Eligible studies were (quasi-)randomized controlled trials and efficacy trials published in English or German with participants up to the
age of 21 years presenting symptoms of mental disorders due to traumatic experiences. The effectiveness of interventions entailing any kind and
extent of caregiver involvement had to be investigated by applying evaluated instruments. PubMed, PsycINFO, ERIC, COCHRANE and PSYNDEX were searched.
RESULT(S): A total of 33 studies with 36 independent samples were retrieved. Child- and parent-reports on PTSD, depression, anxiety, ADHD,
internalizing, externalizing symptoms and behavior problems were analyzed where available. The pooled effect size is significant and robust at post-
treatment for child-reported PTSD, g=- 0.34 (95% CI=- 0.53; - 0.14), parent-reported PTSD, g=- 0.41 (95% CI=- 0.71; - 0.11), child-reported
depression, g=- 0.29 (95% CI=- 0.46; - 0.11), child-reported anxiety, g=- 0.25 (95% CI=- 0.42; - 0.08), and parent-reported internalizing symptoms,
g=- 0.27 (95% CI=- 0.47; - 0.07). Female sex and fulfilling diagnostic criteria appeared as potential moderators. The only significant effect size at
follow-up is found for child-reported PTSD symptoms 12 months post-treatment, g=- 0.37 (95% CI=- 0.67; - 0.07). CONCLUSION(S): Interventions
entailing caregiver involvement revealed greater symptom reductions than control conditions. Determinants of their effectiveness should be examined
further. Copyright © 2022. The Author(s).
Clinical child and family psychology review, 26(1) : 17-
32
- Year: 2023
- Problem: Anxiety Disorders (any), Post Traumatic Stress Disorder, Depressive Disorders
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder), At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Syed-Sheriff,
R. J., Vuorre, M., Riga, E., Przybylski, A. K., Adams, H., Harmer, C. J., Geddes, J. R.
OBJECTIVE: We aimed to compare a co-produced
online intervention encompassing the diverse human stories behind art and artefacts, named Ways of Being (WoB), with a typical museum website, the
Ashmolean (Ash) on negative affect (NA), positive affect (PA) and psychological distress (K10).\rMETHODS: In this parallel group RCT, 463 YP aged 16
-24 were randomly assigned, 231 to WoB and 232 to Ash.\rRESULTS: Over the intervention phase (an aggregate score including all post-allocation
timepoints to day-five) a group difference was apparent in favour of WoB for NA (WoB-Ash n=448, NA -0.158, p=0.010) but no differences were detected
for PA or K10 and differences were not detected at week six. Group differences in NA in favour of WoB were detected in specific subgroups, e.g.
ethnic minorities and males. Across participants (from both groups) mean K10 and NA improved between baseline and six weeks despite increased COVID-
19 restrictions. Trial recruitment was rapid, retention high and feedback positive with broad geographical, occupational and ethnic diversity.
\rCONCLUSIONS: Online engagement with arts and culture has the potential to impact on mental health in a measurable way in YP with high unmet mental
health needs.
Australian & New Zealand Journal of
Psychiatry, 57(5) : 745-757
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Service Delivery & Improvement, Technology, interventions delivered using technology (e.g. online, SMS)
Swee, M. B., Klein, K., Murray, S., Heimberg, R. G.
Objectives: Over the last decade, the mental health of undergraduate students has been of increasing concern and the prevalence of
psychological disorders among this population has reached an unprecedented high. Compassion-based interventions have been used to treat shame and
self-criticism, both of which are common experiences among undergraduate students and transdiagnostic vulnerability factors for an array of
psychological disorders. This randomized controlled study examined the utility of a brief online self-compassionate letter-writing intervention for
undergraduate students with high shame.\rMethod: Participants were 68 undergraduates who scored in the upper quartile on shame. Individuals were
randomly assigned to a 16-day self-compassionate letter-writing intervention (n = 29) or a waitlist control group (n = 39). Participants completed
baseline, post-assessment, and one-month follow-up measures.\rResults: Participants who practiced self-compassionate letter writing evidenced
medium-to-large reductions in global shame, external shame, self-criticism, and general anxiety at post-assessment, and gains were sustained at
follow-up. Additionally, there were trend-level effects for increases in self-compassion and decreases in depression for those who participated in
the intervention.\rConclusions: This study examined the efficacy of self-compassionate letter-writing as a stand-alone intervention for undergraduate
students with high shame. This brief, easily accessible, and self-administered practice may be beneficial for a host of internalizing symptoms in
this population and may support university counseling centers as they navigate high demand for mental health services.
Mindfulness, 14(4) : 854-867
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM)