Disorders - Substance Use Disorders
Roberts, N.
P., Lotzin, A., Schafer, I.
Background: The psychological treatment of comorbid post-traumatic stress disorder (PTSD) and substance use disorder (SUD)
is clinically challenging, and outcomes are often poor. Impact Statement Highlights: For PTSD, evidence was strongest for trauma-focused CBT-based
approaches, but effects were modest. There was little evidence of any added benefit on substance use, beyond that of standard addiction treatments,
for any included intervention. Dropout from treatment was high. (PsycInfo Database Record (c) 2022 APA, all rights reserved) Abstract (Spanish)
Antecedentes: El tratamiento psicologico del trastorno de estres postraumatico (TEPT) comorbido con trastorno por uso de sustancias (TUS) es un
desafio clinico y los resultados suelen ser deficientes. Objetivo: Este articulo describe una revision sistematica y meta-analisis, los cuales
buscaron establecer la eficacia actual para un determinado numero de enfoques psicologicos para adultos y adolescentes, en comparacion con
intervenciones solo para TUS, y otros enfoques activos, siguiendo un protocolo previamente registrado. Metodo: Esta revision siguio las guias PRISMA
y de Colaboracion de Cochrane. Todos los autores realizaron extraccion de datos y evaluacion de riesgo de sesgos usando los criterios de Cochrane.
Los resultados primarios fueron severidad de TEPT y uso de sustancias post-tratamiento. La calidad de los hallazgos fue evaluada utilizando GRADE.
Luego de una busqueda exhaustiva, realizada el 13 de septiembre del 2021, se incluyeron 27 estudios. Resultados: Encontramos un nivel de abandono
relativamente alto en los estudios. En nuestras principales comparaciones no encontramos mayores beneficios en los actuales abordajes de tratamiento
focalizados en mejorar las habilidades de afrontamiento en comparacion con las intervenciones exclusivas para TUS. Encontramos beneficios modestos
para intervenciones centradas en trauma sumada a intervencion para TUS post-tratamiento de TEPT (DMP = -0.36 CI-0.64, -0.08), y a los 6-13 meses para
TEPT (DMP = -0.48 CI-0.81, -0.15) y uso de alcohol (DMP = -0.23 CI -0.44, -0.02). No hubo beneficios para las intervenciones para reestructuracion
cognitiva como grupo, pero encontramos un efecto modesto post-tratamiento para la terapia cognitivo conductual integrada (TCCI) para el TEPT (DMP =
-0.33 CI -0.62, -0.04). Hubo evidencia de algun beneficio para intervenciones enfocadas en trauma sobre las intervenciones centradas en el presente
para TEPT de un solo estudio y para la reduccion del abandono para la participacion incentivada para la intervencion centrada en el trauma de otro
estudio aislado. La mayoria de los hallazgos fueron de muy baja calidad. Conclusion: Concluimos que existe evidencia de que la terapia centrada en el
trauma y la TCCI pueden mejorar el TEPT para algunos individuos, pero muchos pacientes no se comprometen totalmente con el tratamiento y los efectos
de tratamiento promedio son modestos. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
European Journal of Psychotraumatology Vol 13(1), 2022,
ArtID 2041831, 13(1) :
- Year: 2022
- Problem: Post Traumatic Stress Disorder, Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any)
Peters, W., Rice, S., Alvarez-Jimenez, M., Hetrick, S. E., Halpin, E., Kamitsis, I., Santesteban-Echarri, O., Bendall, S.
Aim: Interpersonal trauma
exposures are associated with anxiety, depression, and substance use in youth populations (aged 12-25 years). This meta-analysis reports on the
efficacy of psychological interventions on these symptom domains in addition to post-traumatic stress. Method(s): Following PRISMA guidelines, a
search of electronic databases was performed for randomized controlled trials (RCTs) assessing interventions for young people following interpersonal
trauma exposure. Risk of bias was assessed using the Cochrane Risk of Bias tool. Data were analysed using random-effects meta-analyses. Result(s): Of
the 4832 records screened, 78 studies were reviewed, and 10 RCTs, involving 679 participants (mean age 15.6 years), were analysed. There was a large
pooled effect size for post-traumatic stress (7 studies, g = 1.43, 95% CI [0.37, 2.15], p =.002) and substance use (2 studies, g = 0.70, 95% CI [-
0.11, 1.22], p <.001) and small effect sizes for anxiety (4 studies, g = 0.30, 95% CI [0.10, 0.49], p =.003), and trend-level effect for depression
(10 studies, g = 0.27, 95% CI [0.00, 0.54], p =.052). Heterogeneity was significant for post-traumatic stress and moderate for depression.
Conclusion(s): High-quality RCTs of psychological interventions for anxiety, depression, substance use, and post-traumatic stress symptoms in young
people exposed to interpersonal trauma are scarce. While available studies show either statistically significant or trend-level efficacy for
psychological interventions in reducing these symptoms, wide confidence intervals, heterogeneity and small sample size mean that results need to be
interpreted with caution. Copyright © 2022 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.
, :
- Year: 2022
- Problem: Anxiety Disorders (any), Post Traumatic Stress Disorder, Depressive Disorders, Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any)
Paschall, M. J., Salazar-
Silva, F., Sloboda, Z., Ringwalt, C. L., Grube, J. W.
This group-
randomized trial assessed the effects of a universal prevention training curriculum for school administrators and teachers that focused on effective
strategies to prevent adolescent substance use and related problems. Twenty-eight schools in three regions of Peru were randomly assigned to either
an intervention or control condition (14 schools per condition). Repeated cross-sectional samples of 11 to 19-year-old students participated in four
surveys from May 2018 to November 2019 (N = 24,529). School administrators and teachers at intervention schools participated in a universal
prevention training curriculum focusing on the development of a positive school climate as well as effective policies related to school substance
use. All intervention and control schools were offered Unplugged, a classroom-based substance use prevention curriculum. Outcome measures included:
lifetime drug use; past-year and past-month tobacco, alcohol, marijuana, and other drug use; awareness of school tobacco and alcohol use policies;
perceived enforcement of school policies; school bonding; perceived friends' use of tobacco, alcohol, marijuana and other drugs; and personal
problems in general and problems related to substance use. Multi-level analyses indicated significant reductions in past-year and past-month smoking,
friends' substance use, and problems related to substance use and in general at intervention relative to control schools. Significant increases were
found in intervention vs. control schools related to students' awareness of school substance use policies, perceived likelihood of getting caught
for smoking, and school bonding. These findings suggest that the universal prevention training curriculum and the school policy and climate changes
it promoted reduced substance use and related problems in the study population of Peruvian adolescents.
Journal of Drug Education, 51(3-4) : 82-
100
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Service Delivery & Improvement, Other service delivery and improvement
interventions
Orciari, E. A., Perman-Howe, P. R., Foxcroft, D. R.
AIM: Rising mortality and disease prevalence in the homeless have been largely attributed
to addiction disorders. This review aimed to assess whether Motivational Interviewing (MI) is effective in changing substance misuse behaviours in
the homeless, specifically: 1. reducing substance misuse; 2. increasing addiction treatment linkage; and 3. whether MI effectiveness varied according
to the different levels of social disadvantage within homeless populations.\rMETHOD: Electronic databases and other sources were searched (to July
2021) for relevant randomized trials and comparative studies. Risk of bias in included studies was evaluated using the Cochrane Risk of Bias tool. A
Narrative Synthesis framework was applied to included studies. Moderator variables subgroup analyses were planned a priori. PROSPERO study protocol
registration: CRD42019134312 RESULTS: The searches found 1885 records; after application of inclusion criteria n = 11 studies from 30 articles were
included in the review, all from the United States. There was a paucity of research regarding MI effectiveness for substance misuse outcomes in
homeless populations, with a focus on short-term rather than long-term impacts. Risk of bias was generally low but was high for detection bias in
most studies. MI appeared to be more effective overall amongst adult homeless persons, yielding consistently small effects, and alcohol use
behaviours seemed to be more amenable to change as a result of MI/MET (Motivational Enhancement Therapy) interventions than drug use ones. Limited
evidence with high risk of bias indicated that social gradient may attenuate MI effectiveness within the young homeless population, with no impact in
the most disadvantaged.\rCONCLUSIONS: The review's mixed findings discourage the use of MI as a stand-alone substance use intervention in homeless
populations. Although the review findings did not identify MI effectiveness for substance use according to the external level of social disadvantage
faced by homeless persons, this should be a focus for further research.
International Journal of Drug Policy, 100 : 103524
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Motivational interviewing, includes Motivational Enhancing Therapy
Opara, I., Pierre, K., Assan, M. A., Scheinfeld, L., Alves, C., Cross, K., Lizarraga, A., Brawner, B.
BACKGROUND: The relationship between drug use
and poor sexual health outcomes in Black adolescent females such as diagnoses of sexually transmitted infections, HIV, and early/unwanted pregnancy
has been established in the literature. Yet, very few interventions have been successful in reducing the risk of poor sexual health outcomes and drug
use for adolescent girls. Even more rare are interventions that are catered to specifically to Black girls in the United States, which is a group
that has the highest rates of poorer sexual health outcomes and negative consequences associated with drug use. Therefore, this systematic review
sought to identify and organize interventions that are focused on preventing HIV, STIs, early pregnancy and drug use for and include large samples of
Black girls. Fifteen interventions were identified that met the review's search criteria.\rRESULTS: A total of 15 interventions that were published
between 2005 and 2020 were included in the review. While all but one intervention focused on sexual health outcomes, two interventions infused drug
use education for girls.\rCONCLUSION: This review provides recommendations for sexual health and drug use prevention researchers to engage in an
intersectional framework and concludes with a summary of next steps to guide future research and policy work to address disparities that impact Black
girls.
International Journal of Environmental Research & Public Health [Electronic
Resource], 19(6) : 08
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any)
Mitchell, S.G., Monico, L.
B., Gryczynski, J., Ross, T., Terplan, M., O'Grady, K. E.
Purpose: The Facilitating Change for Excellence in SBIRT (FaCES) is a service package for adolescent
\rprimary care that was developed based on best practices and evidence, but was empirically untested. The aim of this study is to compare the FaCES
intervention to treatment as usual (TAU) for\rrural adolescent primary care patients.\rMethods: In this modified cluster-randomized stepped wedge
design, providers who completed at\rleast 20 adolescent TAU visits received training in the FaCES package in random order. Adolescent\rpatients (N ¼
1,226) waiting for appointments were continuously recruited into the study and\rcompleted a baseline assessment before their scheduled appointment
and an on-line 3-month\rfollow-up. Participants received either FaCES or TAU, depending on whether their provider had\rbeen trained in FaCES. Due to
COVID-19 disruptions, only 14 of the 29 providers were trained\rbefore study recruitment activities ceased.\rResults: More than 80% of the sample
indicated no prior use of tobacco, alcohol, or marijuana at\rstudy entry. The Arm Time interaction failed to reach significance for the substance
use outcomes considered. In the FaCES condition, the group with no prior use had an increased probability\rof substance use at 3-month follow-up,
while the group reporting prior use had a decreased\rprobability of use at follow-up. Participants who reported no use at baseline had an increased
\rprobability of use at follow-up, whether they received the FaCES intervention or TAU.\rDiscussion: This study was unable to demonstrate the
effectiveness of FaCES. Findings suggest\rsome natural movement in substance use risk over time.
Journal of
Adolescent Health, 71(4, Suppl) : S41-S48
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Randomised controlled trials
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other Psychological Interventions
McDanal, R., Parisi, D., Opara, I., Schleider, J. L.
Internalizing problems (e.g., depression, anxiety) and substance use are common among young people and often co-occur. However,
youths face myriad barriers to access needed treatment, and existing evidence-based interventions tend to focus on internalizing problems or
substance use, rather than both simultaneously. Brief interventions that target both problems may, therefore, be an efficient and accessible resource
for alleviating youth difficulties; however, this possibility has been insufficiently evaluated. This systematic review evaluated the intervention
characteristics and quality of six studies spanning 2015 to 2019 that examined intervention effects on internalizing and substance use outcomes.
Based on independent calculations and author reports (respectively), 3-4 interventions significantly reduced youth internalizing symptoms; 3-5
reduced youth substance use; and 2-3 reduced symptoms in both domains. All six interventions identified substance use as a primary target. Four
interventions were administered by interventionists to youths in inpatient, outpatient, primary care, or school settings. The remaining two studies
delivered content through voicemail messages or an online design. Interventions ranged from~15 to 240 min. Results highlight the sparsity and
heterogeneity of youth-focused brief interventions that have evaluated program effects on both internalizing problems and substance use outcomes,
suggesting a clear need for integrated supports that are also designed for accessibility. Future investigations of brief youth-focused interventions
should assess program effects on both internalizing and substance use outcomes; examine mechanisms driving the varied efficacy of identified
interventions; and create, refine, and test interventions with potential to address co-occurring internalizing problems and substance use in young
people. Copyright © 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Clinical child and family psychology review, 25(2) : 339-
355
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Lei, M. K., Brody, G. H., Beach, S. R.
H.
Biological
aging is a common root for multiple diseases causing morbidity and mortality, and trajectories of aging may start early in life. This study was
designed to examine whether a universal family-based substance use preventive intervention to enhance self-control and reduce substance use would
also result in reductions in biological aging among Black youth from the rural South. The Adults in the Making (AIM) program is a randomized
controlled trial with six 2-h sessions for Black youth. The 216 youths agreeing to provide blood at age 22 included 114 who had received the AIM
intervention and 102 who assigned to the control group. We examined accelerated DNA methylation (DNAm)-based aging using a recently developed
measure, \"GrimAge,\" that has been shown to predict the risk of early mortality and that is known to be more strongly affected by substance use than
other DNAm-based aging indices. Relative to those randomly assigned to the control group, those receiving the intervention demonstrated significantly
enhanced self-control, slower increases in substance use, and reduced Grim aging at age 22. Using a bootstrapping method with 1000 replications, we
found a significant indirect effect of AIM on reduced Grim aging through its effect on self-control and substance use. Sensitivity analyses examined
effects using other indices of DNAm-based aging. These findings suggest that a family-based program designed to enhance rural Black youth's self-
control can have beneficial effects on self-control, enhancing young adult health and health behavior, and ultimately decreased mortality risk.
Copyright © 2021 Family Process Institute.
Family
process, 61(2) : 659-673
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention), Universal prevention
-
Treatment and intervention: Psychological Interventions
(any), Skills training, Other Psychological Interventions
Kilmer, J. R.
Objectives: Project PHARM (Personalized Health
Assessment Related to Medications) is a multicampus, collaborative study addressing the nonmedical use of prescription stimulants. Students from 9
colleges and universities across the United States were recruited to document norms of the nonmedical use of prescription stimulants and to evaluate
the efficacy of a web-delivered personalized feedback intervention (PFI) that primarily targeted nonmedical prescription stimulant use (including
norms, perceived benefits of nonmedical use, motives for nonmedical use, and alternatives to nonmedical use) yet also addressed alcohol and cannabis
use. Method(s): The participants were 843 college students, all reporting nonmedical use of prescription stimulants at least once in the past year,
who were randomized to PFI or control following a baseline assessment. Among the participants, 60% identified as female, the average age was 19.9
years, and 64% identified as White. Result(s): Approximately 69% of the sample used prescription stimulants nonmedically 1 to 5 times during the past
6 months, and the modal number of negative consequences endorsed by participants was 0. Perceived norms for past-year nonmedical prescription
stimulant use were significantly reduced among those in the PFI group compared to the control group (p <.001), as were perceived norms for the
percentage of peers with past-month cannabis use (p <.001). There was no effect of the intervention on the perceived number of drinks by the typical
student. Using a series of generalized linear mixed models (negative binomial), the primary behavior addressed in the PFI, past 6-month nonmedical
prescription stimulant use, was significantly reduced for the intervention condition compared to the control group at 6-month follow-up (p <.05).
There were no significant changes in alcohol use or the related consequences, nor were there significant changes in cannabis use or the related
consequences. Conclusion(s): Although the nonmedical use of prescription stimulants is already a relatively low baseline behavior, the PFI
significantly reduced the nonmedical use of prescription stimulants for completers. Participants reported relatively few perceived harms, which may
represent a challenge to delivering an intervention focused on harm reduction. Implications for future prevention and intervention efforts, along
with lessons learned, will be discussed. COLST, STIM, SUD Copyright © 2022
Journal of the American Academy of Child and Adolescent
Psychiatry, 61(10 Supplement) : S334
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Personalised feedback, normative feedback
Hogue, A., Schumm, J. A., MacLean, A., Bobek, M.
This article updates the evidence-based on couple and family therapy interventions for
substance use disorders (SUD) since publication of the previous JMFT reviews in 2012. It first summarizes previous reviews along with findings from
more recent reviews and meta-analytic studies. It then presents study design and methods criteria used to select 13 studies of couple and family
therapy for level of support evaluation. Cumulative level of support designations are then determined for identified treatment approaches. Findings
indicate that systemic family therapy is well-established as a standalone treatment, and behavioral family therapy and behavioral couple therapy are
probably efficacious as standalone treatments and well-established as part of a multicomponent treatment. The article then suggests practice
guidelines with regard to treatment modality considerations and implementation challenges. It concludes with future directions for delivering couple
and family interventions in routine systems of care for SUD.
Journal of Marital & Family Therapy, 48(1) : 178-
203
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Family therapy
Haug, S., Boumparis, N., Wenger, A., Schaub, M. P., Paz-Castro, R.
Background: Addictive behaviors such as
tobacco/e-cigarette smoking, at-risk alcohol consumption, cannabis use or compulsive internet use are common among apprentices. ready4life is a
mobile app-based preventive intervention program for apprentices that promotes life skills and reduces risky behavior. The present study tested the
efficacy of ready4life for addiction prevention among apprentices in Switzerland within a controlled trial. Method(s): Two-arm, cluster-randomized
controlled trial including assessments at baseline and follow-up after 6 months. Participants of the intervention group received coaching by a
conversational agent for 16 weeks. The main outcome measure was a composite score for addictive behaviors, which included (1) at-risk drinking, (2)
tobacco/e-cigarette smoking, (3) cannabis use and (4) problematic internet use. Result(s): A total of 2275 students from 159 vocational school
classes in Switzerland, were invited for study participation. Of these, 1351 (59.4%) students with a mean age of 17.3 years and a male proportion of
56.6% provided informed consent to participate. The follow up assessment at month 6 was completed by 962 (71.2%) study participants. The results
concerning the primary outcome showed a stronger decrease of addictive behaviors between baseline and follow up in the intervention group compared to
the control group. In particular, significant effects were observed for at-risk drinking and problematic Internet use, while no significant effects
were observed for tobacco/e-cigarette smoking and cannabis use. Conclusion(s): The majority of apprentices invited for program participation within
vocational schools participated in the ready4life program for addiction prevention. The mobile app-based coaching was effective in reducing risk
behaviors such as at-risk drinking and problematic Internet use in a group of adolescents who have an especially high risk of engaging in addictive
activities. Copyright © 2022 by the authors.
International Journal of Environmental Research and Public
Health, 19(23) (no pagination) :
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Randomised controlled trials
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Skills training, Personalised feedback, normative feedback, Technology, interventions delivered using technology (e.g. online, SMS)
Harrison, L., Sharma, N., Irfan, O., Zaman, M., Vaivada, T., Bhutta, Z. A.
CONTEXT: Previous reviews of mental health interventions have focused on adolescents (10-19 years), with a paucity of
comprehensive evidence syntheses on preventive interventions for school-aged children (5-10 years). OBJECTIVE(S): To summarize and synthesize the
available evidence from systematic reviews of mental health and positive development interventions for children aged 5-14.9 years in both high-income
(HIC) and low- and middle-income countries (LMIC), with a focus on preventive and promotive strategies. DATA SOURCES: This overview includes all
relevant reviews from OVID Medline, The Cochrane Library, and Campbell Systematic Reviews through December 2020. STUDY SELECTION: We included
systematic reviews that synthesized empirical studies using experimental or quasi-experimental designs to evaluate the effectiveness of interventions
in children aged 5-14.9 years. DATA EXTRACTION: Data extraction and quality assessment were completed independently and in duplicate by two review
authors. The AMSTAR2 tool was used to assess methodological quality. RESULT(S): We included 162 reviews. The greatest evidence was found in support
of school-based universal and anti-bullying interventions in predominantly HIC. Moderate evidence was found for the use of substance abuse
prevention, and early learning and positive development interventions in mixed settings. In LMIC-only contexts, the most promising evidence was found
for positive youth development programs. LIMITATIONS: The review was primarily limited by paucity of high-quality research due to methodological
issues and high heterogeneity. CONCLUSION(S): This overview of reviews highlights the need for further research to consolidate findings and
understand the specific criteria involved in creating positive mental health and development outcomes from the various interventions considered.
Copyright © 2022 by the American Academy of Pediatrics.
Pediatrics, 149(Supplement 5) :
- Year: 2022
- Problem: Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any)