Disorders - depressive disorders
Teng, T., Zhang, Z., Yin, B., Guo, T., Wang, X., Hu, J., Ran,
X., Dai, Q., Zhou, X.
Functioning and quality of life (QOL) are typical outcomes assessed in children and adolescents with major
depressive disorder (MDD); however, meta-analytical evidence remains scarce. The aim of this meta-analysis was to assess functioning and QOL
antidepressant outcomes in this population. Eight electronic databases (PubMed, Cochrane Library, Web of Science, Embase, CINAHL, PsycINFO, LILACS,
and ProQuest Dissertation Abstracts) were searched for double-blind randomized controlled trials (RCTs) up to July 31, 2020. RCTs that compared
antidepressants with placebo for treating functioning and QOL in children and adolescents with MDD were included. Primary outcomes were mean change
scores of functioning and QOL scales from baseline to post-treatment. Subgroup and sensitivity analyses were conducted to examine whether results
were affected by moderator variables (e.g., medication type, age, sample size, and treatment duration). From 7284 publications, we included 17 RCTs
(all 17 assessed functioning and 4 assessed QOL outcomes) including 2537 participants. Antidepressants showed significant positive effects on
functioning (standardized mean difference [SMD] = 0.17, 95% confidence interval [CI] = 0.09-0.25, p < 0.0001) but not on QOL (SMD = 0.11, 95% CI = -
0.02 to 0.24, p = 0.093), with no significant heterogeneity. The subgroup analysis showed that second-generation antidepressants (especially
fluoxetine, escitalopram, and nefazodone), but not first-generation antidepressants, led to significant improvements in functioning. Antidepressants
(especially second generation) improve functioning but not QOL in children and adolescents with MDD. However, well-designed clinical studies using
large samples are needed to confirm these findings.
Transl Psychiatry
Psychiatry, 12(1) : 183
- Year: 2022
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Biological Interventions
(any), Antidepressants
(any)
Tejada-Gallardo, C., Blasco-
Belled, A., Alsinet, C.
The
effectiveness of multicomponent positive psychology interventions (MPPIs) on adolescents' mental health has been studied with the use of standard
procedures throughout the scientific literature. However, little is known about the potential mechanisms underlying the network structure of mental
health following the dual-factor model after an MPPI. We relied on network analysis to explore the reorganization of the connections between mental
health indicators after a school-based MPPI. Adolescents from two high schools in Spain were randomly allocated to the 6-week intervention group
(n=85) or to the control group (n=135). Network analysis showed that the relations between the two differentiated network dimensions of mental health
(i.e. well-being and psychological distress) changed after the intervention. Unlike control participants, emotional well-being was negatively
associated with depression and stress, while psychological well-being was positively related to stress after the intervention. The present study
supports the viability of the network approach in analyzing the connections between mental health indicators as defined by the dual-factor model and
the contribution of MPPIs to change the complex pattern of relations between the dimensions of well-being and psychological distress. Copyright ©
2022 The Authors. Applied Psychology: Health and Well-Being published by John Wiley & Sons Ltd on behalf of International Association of Applied
Psychology.
, 24 :
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions, Positive
psychology
Tefagh, S., Mokaberinejad, R., Shakiba, M., Jafari, M., Salehi, M., , Khayatkashani, M., Shakeri, N.
Ethnopharmacological relevance: Ustukhuddus Alavi is a polyherbal formula which is introduced by Persian
medicine scholars. It is traditionally used to treat brain disorders and is claimed to do so by preprocessing and cleansing the waste products from
the brain. According to Persian medicine, the disposal of brain waste products is necessary for optimal cognitive performance. Aim of the study:
Sustaining optimal cognitive performance is crucial for ideal quality of life and higher academic achievements in high school students. The objective
of this study was to determine the effects of this multi-component herbal product on the cognitive performance and salivary cortisol levels of
adolescent female students. Material(s) and Method(s): The effect of a 6-week randomly assigned Ustukhuddus Alavi versus placebo administration on
cognitive performance was assessed by the paced auditory serial addition test (PASAT) at the baseline and after the 3- and 6-week intake of
Ustukhuddus Alavi or placebo and the one-month follow-up in 86 healthy female high school students in grades 10 and 11. Additionally, we measured the
levels of salivary cortisol of the students pre- and post-intervention. Result(s): Significant mean difference between the Ustukhuddus Alavi and
placebo groups in three of the paced auditory serial addition test (PASAT) subscales, namely mental health (p-value = 0.006), sustained attention
(p-value = 0.001) and mental fatigue (p-value = 0.001), were observed after six weeks. We also found a significant difference between the mean
salivary cortisol level of the two groups after the intervention (p-value = 0.047). Conclusion(s): These findings reveal that the intake of the
multi-ingredient herbal product Ustukhuddus Alavi for six weeks can be helpful for cognitive function and cortisol levels in female high school
students. These positive effects seem to be related to the increase in sustained attention and the decrease in mental fatigue. Copyright © 2022
Elsevier B.V.
, 288 (no pagination) :
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Homeopathic, plant-based medicines
Sunita., Lata, M. Mondal, H., Kumar,
M., Kapoor, R., Gandhi, A.
Background Medical
education is a rigorous formal education with a vast syllabus. Burnout and stresses are common among medical students and more prominent in females.
Female medical students suffer from a higher level of stress than male medical students. For the improvement of physical and mental health,
meditation, pranayama, and yoga are some of the ancient techniques. Meditation is a technique of focusing the mind on a target like an object,
activity, or any thought. Pranayama is an ancient yogic practice focusing on the breath. Yoga is a combination of physical, mental, and spiritual
dimensions that has the potential to improve mental and physical health. Objective This study aimed to find the effect of meditation, pranayama, and
yoga on the improvement of mental health among female undergraduate medical students. Materials and methods This was an interventional study. A total
of 105 females with a median age of 19 years (first quartile - third quartile: 18-20) first-year undergraduate medical students were recruited for
this study. They were randomly allocated to control, meditation, pranayama, and yoga groups. The control group did not practice any form of
meditation, pranayama, or yoga. The rest of the group practiced a designated program for their group, six days a week for 12 weeks. The anxiety,
depression, anger, and sense of well-being were assessed by a validated self-administered questionnaire developed by the Defence Institute of
Physiology and Allied Sciences, New Delhi before starting the study, at six weeks, and at 12 weeks after the intervention. Inter-group levels of
anxiety, depression, anger, and well-being were compared by the Kruskal-Wallis test with Dunn's posthoc test. Intra-group parameters at baseline, at
six weeks, and at 12 weeks after the intervention was tested by Friedman's test. Result The age (years) (p = 0.07), height (cm) (p = 0.98), and
weight (kg) (p = 0.26) of participants among groups were similar. Anxiety, depression, and anger significantly decreased after six weeks in all three
intervention groups. A further decrement was seen after 12 weeks of meditation, pranayama, and yoga. The maximum effect was seen in the yoga group. A
sense of well-being was improved after practicing all types of interventions. However, meditation was found to increase a sense of well-being to the
highest level compared to pranayama and yoga. Conclusion Introduction and sustainment of meditation, pranayama, and yoga programs for first-year
female undergraduate medical students may help reduce anxiety, depression, and anger and promote a sense of well-being. Although a six-week program
helps to improve mental health, a 12-week program helps in further improvement. A yoga program is more effective for improving the mental health of
the students in comparison with pranayama and meditation.
Cureus, 14(9) : e28915
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Meditation, Mind-body exercises (e.g. yoga, tai chi, qigong)
Sun, Y., Kang, Y.
Background: College students' minds are not yet mature, and they are prone to anxiety
in the face of academic or life setbacks. Long term anxiety will cause serious problems in students' mental health, which will lead to emotional
disorders. Affective disorder, also known as mood disorder, is a kind of long-term, serious emotional or mood change disease caused by various
reasons. Affective disorder will greatly affect the normal life and study of college students, and have an adverse impact on their studies and
employment after graduation. Therefore, based on the theory of positive psychology, the study analyzes the students' anxiety factors and emotional
barriers, and uses the digital media communication that integrates the traditional Chinese culture to intervene the students' psychology, alleviate
the students' anxiety, and alleviate the students'emotional barriers. Subjects and methods: In a university, 60 students who signed up for the
experiment were selected as the experimental objects. Using computer information technology to achieve random grouping, two classes were obtained,
which were recorded as the class A and the class B. Among them, the class A used digital media communication that integrated Chinese traditional
culture to intervene students' emotions; The class B used general digital media to interfere with students' emotions. At the end of the experiment,
the intervention effects of the two intervention methods were evaluated by using the scale tool. Result(s): After a period of intervention, the
experimental results show that the digital media communication integrating Chinese traditional culture can better intervene students' psychology and
alleviate their emotional barriers. Conclusion(s): College students' minds are not yet mature, and they are prone to anxiety in the face of academic
or life setbacks, leading to emotional disorders. Digital media communication can help students release their emotions, alleviate anxiety, and then
alleviate emotional disorders. But the traditional digital media communication has many defects. The study proposes to use the digital media
communication which integrates the traditional Chinese culture to intervene students' psychology and alleviate students' anxiety. The experimental
results show that digital media communication, which integrates Chinese traditional culture, can better intervene students' psychology and alleviate
their emotional barriers. Copyright © Medicinska naklada - Zagreb, Croatia.
Psychiatria Danubina, 34(Supplement 4) : 1064-
1069
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other Psychological Interventions, Technology, interventions delivered using technology (e.g. online, SMS)
Sun, C. W., Wang, Y. J., Fang, Y. Q., He, Y. Q., Wang, X., So, B. C. L., Shum, D. H. K., Yan, C.
The therapeutic effect of antidepressants has been demonstrated for anhedonia in patients with depression. However,
antidepressants may cause side-effects, such as cardiovascular dysfunction. Although physical activity has minor side-effects, it may serve as an
alternative for improving anhedonia and depression. We sought to investigate whether physical activity reduces the level of anhedonia in individuals
with depression. Fifty-six university students with moderate depressive symptoms (Beck Depression Inventory total score > 16) were divided into three
training groups: the Running Group (RG, n = 19), the Stretching Group (SG, n = 19), and the Control Group (n = 18). We employed the Monetary
Incentive Delay (MID) task and the Temporal Experience of Pleasure Scale (TEPS) to evaluate hedonic capacity. All participants in the RG and SG
received 8 weeks of jogging and stretching training, respectively. The RG experienced an increase in the level of arousal during anticipation of a
future reward and recalled less negativity towards the loss condition. The SG exhibited enhanced scores on the Anticipatory and Consummatory Pleasure
subscales of the TEPS after training. Moreover, in the RG, greater improvements in anticipatory arousal ratings for pleasure and remembered valence
ratings for negative affect were associated with longer training duration, lower maximum heart rate, and higher consumed calories during training. To
conclude, physical activity is effective in improving anticipatory anhedonia in individuals with depressive symptoms.
, 11(2) : 214-226
- Year: 2022
- Problem: Depressive Disorders
- Type: Controlled clinical trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM)
Soltan, F., Cristofalo, D., Marshall, D., Purgato, M., Taddese, H., Vanderbloemen, L., Barbui, C., Uphoff, E.
Background: An unprecedented number of people around the world are experiencing forced displacement due
to natural or man-made events. More than 50% of refugees worldwide are children or adolescents. In addition to the challenges of settling in a new
country, many have witnessed or experienced traumatic events. Therefore, refugee children and adolescents are at risk of developing mental health
problems such as post-traumatic stress disorder, and require appropriate and effective support within communities. Objective(s): To assess the
effectiveness and acceptability of community-based interventions (RCTs only) in comparison with controls (no treatment, waiting list, alternative
treatment) for preventing and treating mental health problems (major depression, anxiety, post-traumatic stress disorder, psychological distress) and
improving mental health in refugee children and adolescents in high-income countries. Search Method(s): Databases searches included the Cochrane
Common Mental Disorders Controlled Trials Register (all available years), CENTRAL/CDSR (2021, Issue 2), Ovid MEDLINE, Embase, six other databases,
and two trials registries to 21 February 2021. We checked reference lists of included study reports. Selection Criteria: Studies of any design were
eligible as long as they included child or adolescent refugees and evaluated a community-based mental health intervention in a high-income country.
At a second stage, we selected randomised controlled trials. Data Collection and Analysis: For randomised controlled trials, we extracted data
relating to the study and participant characteristics, and outcome data relating to the results of the trial. For studies using other evaluation
methods, we extracted data relating to the study and participant characteristics. W derived evidence on the efficacy and availability of
interventions from the randomised controlled trials only. Data were synthesised narratively. Main Result(s): We screened 5005 records and sought
full-text manuscripts of 62 relevant records. Three randomised controlled trials were included in this review. Key concerns in the risk of bias
assessments included a lack of clarity about the randomisation process, potential for bias is outcome measurement, and risk of bias in the selection
of results. Primary outcomes. There was no evidence of an effect of community-based interventions when compared with a waiting list for symptoms of
post-traumatic stress (mean difference (MD) -1.46, 95% confidence interval (CI) -6.78 to 3.86: 1 study; low-certainty evidence), symptoms of
depression (MD 0.26, 95% CI -2.15 to 2.67: 1 study; low-certainty evidence), and psychological distress (MD -10.5, 95% CI -47.94 to 26.94; 1 study;
very low-certainty evidence). There were no data on adverse events. Secondary outcomes. Three trials reported on short-term changes in child
behaviour, using different measures, and found no evidence of an effect of the intervention versus a waiting list (low to very low certainty). None
of the trials reported on quality of life or well-being, participation and functioning, or participant satisfaction. Authors' conclusions: There is
insufficient evidence to determine the efficacy and acceptability of community-based mental health interventions for refugee children and
adolescents. Copyright © 2022 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cochrane Database of Systematic
Reviews, 2022(5) (no pagination) :
- Year: 2022
- Problem: Anxiety Disorders (any), Post Traumatic Stress Disorder, Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other service delivery and improvement
interventions
Six, S. G., Byrne, K. A., Aly, H., Harris, M. W.
Background: Mental health apps have shown promise in improving mental
health symptoms, including depressive symptoms. However, limited research has been aimed at understanding how specific app features and designs can
optimize the therapeutic benefits and adherence to such mental health apps. Objective(s): The primary purpose of this study is to investigate the
effect of avatar customization on depressive symptoms and adherence to use a novel cognitive behavioral therapy (CBT)-based mental health app. The
secondary aim is to examine whether specific app features, including journaling, mood tracking, and reminders, affect the usability of the mental
health app. Method(s): College students were recruited from a university study recruitment pool website and via flyer advertisements throughout
campus. A total of 94 participants completed a randomized controlled trial in which they were randomized to either customization or no customization
version of the app. Customization involved personalizing a virtual avatar and a travel vehicle to one's own preferences and use of one's name
throughout the app. Participants completed a 14-day trial using a novel CBT-based mental health app called AirHeart. Self-report scores for
depressive symptoms, anxiety, and stress were measured at baseline and after the intervention. Postintervention survey measures also included
usability and avatar identification questionnaires. Result(s): Of the 94 enrolled participants, 83 (88%) completed the intervention and
postintervention assessments. AirHeart app use significantly reduced symptoms of depression (P=.006) from baseline to the end of the 2-week
intervention period for all participants, regardless of the customization condition. However, no differences in depressive symptoms (P=.17) or
adherence (P=.80) were observed between the customization (39/83, 47%) and no customization (44/83, 53%) conditions. The frequency of journaling,
usefulness of mood tracking, and helpfulness of reminders were not associated with changes in depressive symptoms or adherence (P>.05). Exploratory
analyses showed that there were 3 moderate positive correlations between avatar identification and depressive symptoms (identification: r=-0.312,
P=.02; connection: r=-0.305, P=.02; and lack of relatability: r=0.338, P=.01). Conclusion(s): These results indicate that CBT mental health apps,
such as AirHeart, have the potential to reduce depressive symptoms over a short intervention period. The randomized controlled trial results
demonstrated that customization of app features, such as avatars, does not further reduce depressive symptoms over and above the CBT modules and
standard app features, including journal, reminders, and mood tracking. However, further research elucidating the relationship between virtual avatar
identification and mental health systems is needed as society becomes increasingly more digitized. These findings have potential implications for
improving the optimization of mental health app designs. Copyright © 2022 by the Author(s).
JMIR Mental Health, 9(8) (no
pagination) :
- Year: 2022
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Technology, interventions delivered using technology (e.g. online, SMS), Other service delivery and improvement
interventions
Singh, G., Narang, I., Marwaha, R.
Objectives: The US Surgeon General has issued an advisory to highlight the urgent need
to address the nation's youth mental health crisis. The prevalence of depression in children and adolescents has been increasing; it is reported
that 15% of adolescents have MDD. There is a shortage of pediatric mental health providers. Access to care is a major concern, and the majority of
patients are seen by primary care physicians (PCPs). We conducted a systematic review of RCTs comparing integrated care with the usual care provided
in primary care clinics in pediatric patients diagnosed with depression. Method(s): A systematic search of PubMed and PsycINFO was conducted using
the following keywords: pediatric integrated care, depression, collaborative care, RCT. The inclusion criteria were children/adolescents with
depression receiving treatment, and RCTs comparing integrated care with usual care in pediatric clinics. The exclusion criteria were adults and
systematic/literature reviews. Five studies were identified and reviewed. Result(s): A 2005 trial by Asarnow et al showed that patients receiving
integrated care intervention reported lesser depressive symptoms, higher satisfaction with care, and better access. In a 2014 RCT by Richardson et
al, those receiving collaborative care compared to usual mental health care in pediatric clinics had greater decreases in depression scores measured
by the Children's Depression Rating Scale-Revised (CDRS-R) at 12 months and were more likely to have a depression response and remission. A 2017
trial by Weersing et al showed that patients getting pediatric-based brief behavioral therapy (BBT) intervention for anxiety and depression in
primary care clinics had better results with symptoms compared to those in assisted referral to care (ARC) to outpatient mental health care. A 2020
trial by Brent et al followed up on this study and showed that BBT continued to be superior to ARC at 5 months after treatment completion, yet with
greater superiority in the case of anxiety than depression. Another 2017 trial by Mufson et al suggested that a stepped collaborative care treatment
model delivering interpersonal psychotherapy for depressed adolescents (SCIPT-A) had greater reduction of depression symptoms and improvement in
overall illness severity as compared to enhanced treatment as usual (E-TAC). Conclusion(s): Integrated care has been shown to have superior results
in pediatric patients diagnosed with depression and is an approach that can be widely adopted to provide better mental health care and access. DDD,
ADOL, RCT Copyright © 2022
Journal of the American Academy of Child and Adolescent Psychiatry, 61(10
Supplement) : S192
- Year: 2022
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Service Delivery & Improvement, Other service delivery and improvement
interventions
Shin, J. H., Kim, C. S., Cha, L., Kim, S., Lee,
S., Chae, S., Chun, W. Y., Shin, D. M.
Dark chocolate has long been recognized for its mood-altering properties; however, the evidence regarding the
emotional effects of daily dark chocolate intake is limited. Therefore, we aimed to investigate the effects of dark chocolate intake on mood in
everyday life, with special emphasis on the gut-brain axis. Two different dark chocolates (85% and 70% cocoa content) were tested in this study. In a
randomized controlled trial, healthy adults (20-30 y) consumed either 30 g/d of 85% cocoa chocolate (DC85, n=18); 70% cocoa chocolate (DC70, n=16);
or no chocolate (control group, CON; n=14); for 3 weeks. Mood states were measured using the Positive and Negative Affect Schedule (PANAS). Daily
consumption of dark chocolate significantly reduced negative affect in DC85, but not in DC70. To assess the association between the mood-altering
effects of dark chocolate and the gut microbiota, we performed fecal 16S rRNA sequencing analysis for the DC85 and CON groups. Gut microbial
diversity was significantly higher in DC85 than CON (P<.05). Blautia obeum levels were significantly elevated and Faecalibacterium prausnitzii levels
were reduced in DC85 compared to CON (P<.05). Furthermore, we found that the observed changes in negative affect scores were negatively correlated
with diversity and relative abundance of Blautia obeum (P<.05). These findings indicate that dark chocolate exerts prebiotic effects, as evidenced by
its ability to restructure the diversity and abundance of intestinal bacteria; thus, it may improve negative emotional states via the gut-brain axis.
Copyright © 2021 The Author(s)
, 99 (no
pagination) :
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Dietary advice, dietary change, Other complementary & alternative
interventions
Scott, K., Becker, S. J., Helseth, S. A., Saldanha, I. J., Balk, E. M., Adam, G. P., Konnyu, K. J., Steele, D. W.
BACKGROUND: Co-occurring mental health and substance use (SU) disorders among adolescents are common, with two-thirds of adolescents
who seek SU treatment also requiring support for mental health. Primary care physicians play a key role in the pharmacological treatment of mental
health disorders among adolescents, however, little is known about the impact of these treatments on SU outcomes. OBJECTIVE(S): This systematic
review summarizes the evidence regarding commonly used pharmacotherapy interventions for mental health and their impact on adolescent SU. METHOD(S):
Literature searches were conducted across five databases as part of a larger systematic review of adolescent SU interventions. Studies were screened
for eligibility by two researchers, and study data were extracted regarding study design, patient and treatment characteristics and results. Risk of
bias analyses and qualitative syntheses were completed to evaluate the strength of the evidence and the impact of pharmacotherapy on SU outcomes.
RESULT(S): Ten randomized controlled trials exploring seven pharmacotherapies met criteria for inclusion. All studies had low to moderate risk of
bias. Four studies evaluated pharmacotherapy for co-occurring depression and SU, three evaluated attention deficit hyperactivity disorder and SU, and
three evaluated bipolar disorder and SU. Five of the 10 studies also included a behavioural intervention. We found no evidence that pharmacotherapy
for co-occurring mental health diagnoses impacted SU. CONCLUSION(S): Family medicine clinicians prescribing pharmacotherapy for mental health should
be aware that additional interventions will likely be needed to address co-occurring SU. Copyright © The Author(s) 2021. Published by Oxford
University Press. All rights reserved.For permissions, please e-mail: [email protected].
Family Practice, 39(2) : 301-310
- Year: 2022
- Problem: Bipolar Disorders, Depressive Disorders, Suicide or self-harm with comorbid mental disorder, Substance Use Disorders (any)
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Biological Interventions
(any), Selective serotonin reuptake inhibitors (SSRIs), Antidepressants
(any), Atypical Antipsychotics (second
generation), Anticonvulsants/mood stabilisers (excl. lithium), Lithium, Medications used to treat substance abuse
Schniering, C. A., Einstein, D., Kirkman, J. J. L., Rapee, R. M.
OBJECTIVE: Adolescents experiencing both anxiety and mood disorders show greater life impairment than those with either disorder
alone. The aim of this study was to evaluate the efficacy of an online cognitive behavior therapy (CBT) program for these comorbid youth.\rMETHODS:
Ninety-one adolescents aged 12 to 17 years (M = 14.29, S.D. = 1.62; 66% female) participated if they met DSM-5 criteria for both an anxiety and
depressive disorder. Diagnoses were assessed by structured interview and participants also completed measures of symptoms, negative thoughts, and
life interference. Participants were randomly allocated to either active treatment (n = 45) or wait (n = 46). Treatment comprised access to an 8-
module, online program and was supported by 8, 30-minute telephone sessions with a therapist and the youth, of which the caregiver participated in
four.\rRESULTS: Treated participants showed significantly greater reduction than waiting participants on the primary outcome: total number of
disorders and were more likely to remit from all anxiety and mood disorders (43.8% vs 20.9%). Secondary outcomes covering symptoms of anxiety and
depression showed similar group by time differences, but there was no significant group by time interaction on life interference.\rCONCLUSIONS: This
brief, easily accessible, online intervention that requires relatively low levels of therapist time showed promising impact for a very impaired
population.\rREGISTRATION: This trial was registered on the ANZ clinical trials registry-ACTRN12616000139471.
, 311 : 88-
94
- Year: 2022
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Technology, interventions delivered using technology (e.g. online, SMS)