Disorders - depressive disorders
Shelemy, L., Harvey, K., Waite, P.
A large proportion
of emotional problems begin in adolescence and negatively impact quality of life into adulthood. There have been multiple teacher-delivered,
classroom-based programs created to reduce internalizing problems amongst young people. This meta-analysis and systematic review aims to examine the
effectiveness of teacher-delivered interventions for depression, anxiety, post-traumatic stress disorder (PTSD) and obsessive-compulsive disorder
(OCD) symptoms in adolescents, and a range of factors that may impact outcomes. Database searches were conducted from PsycInfo, Medline (PubMed),
Scopus, Cochrane Library and the British Educational Index (database inception to January 2020). Quality assessment of studies used the EPHPP Quality
Assessment Tool. Fifty-two studies were identified that quantitatively assessed, via controlled design, intervention effects on internalizing
disorder symptoms. Three meta-analyses found teacher-delivered interventions were significantly better than control conditions at improving
depression (g = -0.12), anxiety (g = -0.13) and PTSD symptoms (g = -0.66) in students. Improvements were only maintained at follow-up for anxiety
symptoms and no effect sizes reached a 'small' threshold. However, the effect sizes were 'moderate' within the context of universal prevention
programs for young people. No interventions measured OCD outcomes. Improved outcomes were associated with interventions that lasted up to 16 weeks,
had 45-90 minute long sessions and included two or more days of teacher training. Future studies should report number of sessions taught, quality of
teacher training and fidelity of intervention. Analysis of outcomes for participants with high versus low baseline mental health scores would enable
a better understanding of for whom interventions are most effective. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
Mental Health and Prevention Vol 19 2020, ArtID 200182, 19 :
- Year: 2020
- Problem: Anxiety Disorders (any), Obsessive Compulsive Disorder, Post Traumatic Stress Disorder, Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Skills training, Mindfulness based
therapy
Seppala, E. M., Bradley, C., Moeller,
J., Harouni, L., Nandamudi, D., Brackett, M. A.
This study aimed to address the decline in
mental health on U.S. university campuses by examining the effects of three interventions. University students suffer from high levels of anxiety,
depression, and suicide. Counseling centers on university campuses are struggling to meet increased demand. The cost to students and universities
could be buffered by offering preventative, psychoeducational, and skill-building training programs that promote mental health and psychological
thriving. To date, the research literature has not yielded systematically evaluated and recommendable preventative mental health and well-being
programs for university students. In a registered, randomized controlled trial, 131 university students were either placed in a non-intervention
control group (N = 47) or received training in one of three 30-hour, eight-week semester-long well-being programs: SKY Campus Happiness (\"SKY\"; N =
29), Foundations of Emotional Intelligence (\"EI\"; N = 21) or Mindfulness-Based Stress Reduction (\"MBSR\"; N = 34). Compared to the control group
and controlling for variance of baseline measurements and multiple comparisons, SKY Campus Happiness showed the greatest impact, benefiting six
outcomes: depression, stress, mental health, mindfulness, positive affect and social connectedness. EI benefited one outcome: mindfulness. The MBSR
group showed no change. Delivering SKY or EI to university students may be a cost-effective and efficient way to proactively and preventatively
address mental health for university students and reduce the financial strain on universities. (PsycInfo Database Record (c) 2023 APA, all rights
reserved)
Frontiers in Psychiatry Vol 11 2020, ArtID 590, 11 :
- Year: 2020
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Psychological Interventions
(any), Other Psychological Interventions, Mindfulness based
therapy, Mind-body exercises (e.g. yoga, tai chi, qigong)
Saw, J. A., Tam, C. L., Thanzami, V., Bonn, G.
This study
investigates the effectiveness of the school-based Shine Through Any Roadblocks (STAR) CBT intervention, by a screening conducted on 634 students
from eight secondary schools in Malaysia. Participants (n = 85) who fulfilled the eligibility criteria were assigned randomly to either the
intervention group (n = 42) or the assessment-only waitlist control group (n = 43). The intervention consisted of eight group-based sessions over a
period of 2 months. Sessions were 60-min each and conducted according to the STAR module. Outcome measures (depressive symptoms and automatic
negative thoughts) were administered at five intervals: baseline/pre-intervention, mid-intervention, post-intervention, 1-month after intervention,
and 3-months after intervention. Results showed significant and lasting lower levels of depressive symptoms and automatic negative thoughts in the
intervention group, indicating that the STAR intervention could be an effective means of reducing depressive symptomatology among adolescents.
Clinical implications for the Malaysian secondary school context are further discussed. (PsycInfo Database Record (c) 2022 APA, all rights
reserved)
Frontiers in Psychiatry, 11 : ArtID
565896
- Year: 2020
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT)
Ng, M. Y., DiVasto, K. A., Cootner, S., Gonzalez, N., Weisz, J. R.
Psychotherapy for youth depression is only modestly efficacious. Investigating treatment mediators may guide improvement. Among 46
randomized trials of cognitive behavioral therapy and interpersonal psychotherapy with depressed youths, 74% measured candidate mediators (CMs), but
only 17% analyzed CMs as mediators. Although four significant CMs emerged, findings were sparse, conflicting, and clouded by methodological issues.
We see enormous untapped opportunity in the ample data collected but not yet analyzed using recommended methods. We propose exploiting existing data
using mediation meta-analysis, broadening the range of CMs and the rigor of assessments, making measurement longitudinal and idiographic to clarify
temporal precedence of CMs over outcomes and detect individual differences, and markedly altering journal and funder policies to promote change
process and mechanism research. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Impact Statement We reviewed candidate mediators that
may explain how psychotherapies for youth depression work and found that they were often measured but rarely tested in research trials. Although
several significant mediators were found in a sample of largely cognitive behavioral therapy trials, these findings are inconclusive given the
limited strength of the evidence. We propose changing scientific practices and policies to fully examine existing data and to collect and analyze new
data on candidate mediators using methods that maximize information value. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
, : No Pagination
Specified
- Year: 2020
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Interpersonal therapy (IPT)
Miller, M.
B., Hall, N., DiBello, A. M. Park, C.
J., Freeman, L., Meier, E., Leavens, E. L., Leffingwell, T. R.
Background:
Personalized normative alcohol feedback (PNF) is associated with decreased alcohol use among\ryoung adults. However, limited research has examined
the influence of depressive symptoms on PNF efficacy.\rThis study examined symptoms of depression as a moderator of college student response to a
computerized PNF\rintervention for alcohol use.\rMethods: College students (N = 212, 59% female) who reported drinking in a typical week completed
baseline\rand one-month assessments as part of a previously published intervention trial. We randomized participants to\ralcohol PNF (n = 153) or
assessment only (n = 59). We used regression models to examine the interaction\rbetween PNF and symptoms of depression on alcohol outcomes at one-
month follow-up.\rResults: One in four participants screened positive for clinically significant symptoms of depression. Depressive\rsymptoms did not
moderate intervention effects on drinking quantity. However, PNF was only associated with\rreduced frequency of heavy episodic drinking and lower
probability of any alcohol-related consequence in the\rcontext of mild to moderate (not minimal) symptoms of depression.\rConclusions: PNF is more
effective than assessment alone in reducing drinking quantity, regardless of symptoms\rof depression. However, it may only be more effective in
decreasing frequency of heavy episodic drinking and\rthe probability of alcohol-related consequences among those experiencing mild to moderate (as
opposed to\rminimal) symptoms of depression. Alcohol intervention trials should assess symptoms of depression and consider\rthem in data
analysis.
Journal of Substance Abuse Treatment Vol 115 2020, ArtID
108038, 115 :
- Year: 2020
- Problem: Depressive Disorders, Alcohol
Use
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other Psychological Interventions, Personalised feedback, normative feedback, Technology, interventions delivered using technology (e.g. online, SMS)
Kip, A, Priebe, S., Holling, H., Morina, N.
Millions of refugees around the globe suffer from posttraumatic stress
disorder (PTSD) and/or depression. We conducted a meta-analysis of randomized controlled trials (RCTs) to determine the efficacy of psychological
interventions for PTSD and/or depression in refugees. The meta-analysis was registered on the PROSPERO database (CRD42017071384). A search using the
Medline, PsycINFO, and PILOTS databases was conducted in January 2019, resulting in 17 RCTs, of which 14 were conducted with adult refugees (1,108
participants) and 3 with young refugees (<18 years; 151 participants). Further inclusion criteria were at least 10 participants completing an active
psychological intervention for PTSD, depression, or both and less than 50% of participants receiving concurrent psychotropic drugs. Random effects
models showed that active interventions for adult PTSD yielded a medium to large aggregated effect size (g = 0.77; 95% confidence interval [CI]
[0.26, 1.28]) at posttreatment when compared with passive and active control conditions. Active interventions for adult depression also produced
large controlled effect sizes at posttreatment (g = 0.82; 95% CI [0.24, 1.40]). The effects appeared to persist over the average follow-up period of
6 months. The findings suggest that psychological interventions can effectively reduce symptoms of both PTSD and depression in adult refugees.
However, the considerable heterogeneity between studies indicates that the efficacy may vary significantly. Future studies should aim to explore the
substantial heterogeneity in effect sizes between studies with adult refugees. Additionally, more trials with young refugees suffering from PTSD or
depression are needed to determine treatment efficacy for this population. Copyright © 2020 The Authors. Clinical Psychology & Psychotherapy
published by John Wiley & Sons Ltd.
Clinical Psychology & Psychotherapy, 27(4) : 489-
503
- Year: 2020
- Problem: Post Traumatic Stress Disorder, Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any)
Haruvi Catalan, L.
In recent years,
suicidal behaviors have shown substantial increase worldwide. This trend is also prominent in Israel and has led to a dramatic increase in mental
health treatment demand resulting in long wait times and low treatment acceptance rate. To address the critical need in crisis intervention for
children and adolescents at suicidal risk we developed an ultra-brief acute crisis intervention, based on Interpersonal Psychotherapy (IPT). IPT is
an evidence-based intervention for various psychopathologies among different age groups. The current adaptation of IPT-A is comprised of five weekly
sessions, followed by monthly follow-up caring email contacts to the patients and their parents, over a period of 3 months. This paper aims to review
the theoretical foundation of this intervention, describe the research design, and present preliminary results of a pilot study. Preliminary Results
from our samples of 26 adolescents indicate meaningful trends for both the suicidal ideation (SIQ) and depression (MFQ) outcome measures. Significant
interaction was found concerning suicidal ideation but not for depression. Main limitations include small sample size and stratified controls. The
treatment appears to be safe, feasible and acceptable and initial results show promising trends to support further study of the approach. © Copyright
© 2020 Haruvi Catalan, Levis Frenk, Adini Spigelman, Engelberg, Barzilay, Mufson, Apter, Benaroya Milshtein, Fennig and Klomek.
Frontiers in Psychiatry, 11 (no
pagination) :
- Year: 2020
- Problem: Depressive Disorders, Suicide or self-harm behaviours (excluding non-suicidal self-harm), Suicide or self-harm with comorbid mental disorder
- Type: Controlled clinical trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Interpersonal therapy (IPT)
Garde Gonzalez, J., Lopez, V., Orosa-Duarte, A., Mediavilla, R., Munoz-Sanjose, A., Palao, A., Bravo-Ortiz, M. F., Bayon, C., Rodriguez-Vega, B.
Introduction: Studies have associated students from Medicine and other healthcare degrees with high levels of stress
and depression. This puts at risk both their mental health and the quality of physician-patient relationship. Mindfulness-Based Stress Reduction
(MBSR) program has been shown to improve psychological wellbeing and to reduce rumination; however, it seems unclear if digital programs have the
same effect. Objective(s): To compare the effectiveness of a mindfulness smartphone app versus an adapted version of the MBSR program among
healthcare students. Method(s): A parallel-group, single-blind, randomised (1:1:1), controlled trial was designed. 140 students of Medicine, Nursing,
Psychology and Nutrition were allocated to either the app program, the in-person program, or a waitlist. The assessment of depressive symptoms was
included though the Beck Depression Inventory at baseline and post-intervention (8 weeks). Result(s): 86 participants completed BDI at both times and
an intention-to-treat analysis was performed. Depressive levels changed from 7.21 (SD 6.08) to 4.07 (SD 4.44) in the app group, and from 7.11 (SD
6.62) to 5.26 (SD 5.21) in the in-person group. ANOVA test did not find a significant difference for depression among the three arms. Conclusion(s):
Only a tendency to significance was found for both the app and the in-person program for the reduction of depressive symptoms. Most participants
presented minimum levels of depression at baseline, so a floor effect might be considered as an explanation. Future studies are needed to determine
the effect of mindfulnessbased programs on the depression levels of healthcare students.
European Psychiatry, 63(Supplement 1) : S383-S384
- Year: 2020
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Mindfulness based
therapy, Technology, comparing delivery mode (e.g. online vs. face-to-face)
Amanvermez, Yagmur, Rahmadiana, Metta, Karyotaki, Eirini, de-Wit,
Leonore, Ebert, David D., Kessler, Ronald C., Cuijpers, Pim
This systematic review and meta-analysis aimed to examine the effects of stress management interventions in reducing
stress, depression, and anxiety among college students. Two separate meta-analyses of randomized controlled trials were conducted using the random-
effects model, for students with high-stress levels (n = 8) and for the unselected college student population (n = 46). Overall, main results showed
moderate intervention effects for stress, depression, and anxiety in both groups. Subgroup analyses yielded significant differences related to the
theoretical background, the type of control condition, and the length of the intervention in trials targeting students with high-stress levels.
However, these subgroup differences, except for the theoretical background, were not observed in trials including unselected samples. Our results
suggest that stress management interventions may be effective in reducing distress among college students. (PsycInfo Database Record (c) 2022 APA,
all rights reserved) Impact Statement Public Health Significance Statement-Symptoms of stress are common among college students. Stress management
programs are provided to help students in reducing stress. The present study showed that stress management programs have the potential to decrease
stress and prevent mental health problems in higher education. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
, : No
Pagination Specified
- Year: 2020
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Other Psychological Interventions
Trebaticka, J., Matzova, Z., Hradecna, Z., Guschina,
I., Garaiova, I., Suba, J., Durackova, Z.
Background and aims.- The prevalence of mood disorders in children has an increasing trend. Omega-3 fatty acids (FA) are shown as a
promising adjuvant treatment of depressive disorder in children. The primary objective of this pilot, single-centre, randomized, double-blind
controlled study was to investigate the levels of Omega-3 and Omega-6 FA in serum and their ratio in children with depression before and after fish
oil emulsion administration. Methods.- 41 children (11 to 17 years) were randomised 1:1 to the Omega-3 FA or Omega-6 FA groups. Patients were
clinically investigated with CDI score (Children's Depression Inventory) every two weeks during 12 weeks of intervention. The levels of omega- 3
(eicosapentaenoic acid- EPA, docosahexaenoic acid-DHA) and omega-6 FA in serum were determined by capillary FID-gas chromatography. Results.- CDI
scores decreased after the omega-3 FA supplementation by 27% compared to omega-6 FA (13%). The EPA and DHA levels were lower in depressed children,
unlike in 20 healthy children. After supplementation with omega-3 FA, the level of EPA has risen to 500% and DHA to 250% of the original values. The
omega- 6/omega-3 ratio was 25.5: 1 for depressed children and 18: 1 for the control group (p = 0.021). After 6-week omega-3 supplementation, the
omega-6/omega-3 ratio was reduced to 8.8: 1 (p < 0.0001), unlike in omega-6 supplementation where the omega-6/omega-3 ratio remained unchanged (24.5:
1). The ratio omega-6/omega-3 positively correlated with CDI score (p = 0.003). Conclusions.- The omega-3 FA could be a suitable adjuvant therapy for
reducing the severity of depression and the omega-6/omega-3 FA ratio. (APVV-grant 15-0063).
European
Psychiatry, 56(Supplement 1) : S49
- Year: 2019
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention, At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Fish oil (Omega-3 fatty acids), Omega 3 fatty
acids (e.g. fish oil, flax oil)
Remberk, B., Kalwa, A., Niwinski,
P., Popek, L.
Background and aims.- Physical activity (PA) has therapeutic effect an depressive symptoms. However PA efficacy has not
been studied in adolescent inpatient sample. Aim of the study is assessment of PA efficacy on depressive symptoms in adolescent inpatients. Methods.-
Consecutive adolescent inpatients with depression confirmed by Child Depression Inventory and/or Hamilton Depression Scale were included to the
study. All participants have been treated according to the state-of-art recommendations with the add-on study intervention. Each patient has been
randomly assigned either to physical activity (PA) or occupational therapy (OC) group. The intervention was administered three times a week during
four weeks. At the baseline and after four weeks psychopathological symptoms were assessed with composite battery, including Kutcher Adolescent
Depression Scale (KADS), Children Depression Inventory (CDI), Clinical Global Impression Scale-Severity (CGI-S) and Improvement (CGI-I) and self-
rated Global Impression Scale (PGI). Improvement was defined as the difference between baseline and final score. Results.- The project is in
progress. By now 10 patients in the PA group and 6 in the OC group completed the study. For the whole group n = 16 statistically significant
improvement in all scales was observed (p < 0.05). In group comparison statistical analysis was not performed due to small sample sizes. Mean
improvement in PA and OC groups was respectively: CDI 12.7 +/- 7.4 versus 3.4 +/- 5.0; KADS 6.9 +/- 4.4 versus 3.8 +/- 2.6; PGI 2,3 +/- 2.3 versus
1,2 +/- 0.8; CGI 1.1 +/- 0.6 versus 1.3 +/- 1.0 and CGI-I score was 2.3 +/- 0.7 and 2.3 +/- 0.5. Conclusions.- Physical activity is non-invasive
intervention easy to administer in inpatient setting. Preliminary results, although promising, should be interpreted with cautious. Larger sample is
needed.
European Psychiatry, 56(Supplement
1) : S623
- Year: 2019
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Physical activity, exercise, Other complementary & alternative
interventions
Lee, J.
Background and aims.- Cognitive model of
depression suggests that information processing such as attention, interpretation and memory bias respectively affect depressive symptoms. The
combined hypothesis indicating that interpretation, attention and memory biases does not operate in isolation but influence depressive symptoms by
working together is also of special interest. The present study aimed to investigate whether positive interpretation biases generated by CBM training
would be helpful in recalling positive memory. Methods.- Seventy depressed graduate and undergraduate students were allocated to one of two groups
(intervention group with CBM training vs. control group without CBM training). Four sessions of computer based CBM trainings were delivered to the
intervention group over the two week periods. Both groups completed preand post-tests: an ambiguous interpretation bias task, memory task and self-
reported mood measurements. Results.- The CBM training group aiming to promoting positive interpretations reported decreased sadness and tension
whereas the control group did not show such changes in mood. In addition, the CBM training group interpreted ambiguous stimuli in a more positive
manner and recalled more positive memory, compared to the control group. Conclusions.- CBM training for positive interpretation might be helpful to
memorize what the depressed experience in daily life in a more positive way. Our results support the combined hypothesis indicating that
interpretation biases affect memory biases. A future study warrants to confirm the opposite direction as well: memory biases would affect
interpretation biases.
European Psychiatry, 56(Supplement
1) : S472
- Year: 2019
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Attention/cognitive bias
modification