Disorders - Depressive Disorders
Compas, B. E., Forehand, R., Thigpen, J., Hardcastle, E., Garai, E., McKee, L., Keller, G., Dunbar, J. P., Watson, K. H., Rakow, A., Bettis, A., Reising, M., Cole, D., Sterba, S.
Objective: Building on an earlier
study (Compas, Forehand, Thigpen, et al., 2011), tests of main effects and potential moderators of a family group cognitive-behavioral (FGCB)
preventive intervention for children of parents with a history of depression are reported. Method: Assessed a sample of 180 families (242 children
ages 9-15 years) in a randomized controlled trial assessed at 2, 6, 12, 18 and 24 months after baseline. Results: Significant effects favoring the
FGCB intervention over a written information comparison condition were found on measures of children's symptoms of depression, mixed
anxiety/depression, internalizing problems, and externalizing problems, with multiple effects maintained at 18 and 24 months, and on incidence of
child episodes of major depressive disorder over the 24 months. Effects were stronger for child self-reports than for parent reports. Minimal
evidence was found for child age, child gender, parental education, parental depressive symptoms, or presence of a current parental depressive
episode at baseline as moderators of the FGCB intervention. Conclusions: The findings provide support for sustained and robust effects of this
preventive intervention. (PsycINFO Database Record (c) 2016 APA, all rights reserved) (journal abstract).
Journal of Consulting & Clinical Psychology, 83(3) : 541-
553
- Year: 2015
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Psychoeducation
Clarke, G., McGlinchey, E. L., Hein,
K., Gullion, C. M., Dickerson, J. F., Leo, M. C., Harvey, A. G.
We tested whether augmenting conventional
depression treatment in youth by treating sleep issues with cognitive behavioral therapy for insomnia (CBT-I) improved depression outcomes. We
randomized youth 12-20 years of age to 10 weekly sessions of a sleep hygiene control condition (SH) combined with CBT for depression (CBT-D) (n =
20), or an experimental condition consisting of CBT-I combined with CBT-D (n = 21). We assessed outcomes through 26 weeks of follow-up and found
medium-large effects favoring the experimental CBT-I arm on some sleep outcomes (actigraphy total sleep time and Insomnia Severity Index \"caseness
\") and depression outcomes (higher percentage recovered, faster time to recovery), but little effect on other measures. Total sleep time improved by
99 min from baseline to week 12 in the CBT-I arm, but not in the SH arm. In addition, our pilot yielded important products to facilitate future
studies: the youth-adapted CBT-I program; the study protocol; estimates of recruitment, retention, and attrition; and performance and parameters of
candidate outcome measures. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
Behaviour Research & Therapy, 69 : 111-
118
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT)
Chahar, A., Gulati, R., Sharma, J., Likhar, N., Dang, A.
Objectives: The increasing
prevalence of mental health disorders in children is a growing concern in India. Community based therapy, such as school based therapy (SBT) and
psychotherapy (PT) is used in the treatment. This paper aims to investigate the disease burden of mental health disorders, and assess the clinical
and economic impact (by cost-effectiveness analysis) of SBT and PT on the symptoms of depression in Indian children aged below 15 years. Methods:
Health technology assessment by systematic review of published literature. An electronic literature search was performed in Cochrane Review,
Elsevier, PubMed and Medline databases for randomized controlled trials and cohort studies pertaining to community based therapies, particularly SBT
and PT, in Indian children aged below 15 years suffering from depression. RevMan 5.0 was used for data analysis and quantitative data synthesis.
Cochrane Review Manager's Risk of Bias Table was used to assess the risk of bias. Results: Out of 32 studies which were screened, 6 studies
involving a total of 1,375 participants (377 received SBT, 325 received PT, 673 received neither) were included. In comparison with no therapy, SBT
significantly reduced symptoms of depression: standard mean difference (SMD) -0.20 (95% confidence interval (CI) -0.35 to -0.04); PT significantly
reduced symptoms of depression: SMD -0.64 (95% CI -1.44 to 0.16). Economic burden: a total of 95,295.50 DALY/year was lost due to the condition in
specific the patient population. Assuming the cost of PT as INR 300 (US$ 4.75) per session, INR 962,000 (US$ 15220.341) was required per year to
avert 1 DALY. By reducing the cost of each session by INR 50 (US$ 0.80), the PT can be made more cost-effective. Conclusions: SBT and PT are
clinically and economically effective in reducing the symptoms of depression in Indian children aged below 15 years suffering from depression.
Value in Health, 18(3) : A275
- Year: 2015
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any)
Cheng, F. K.
Mental disorders affect not only individual
well-being but also community health, which pushes mental care professionals to investigate various solutions to accommodate different needs. The
exercise of Baduanjin, a form of Qigong, facilitates improvements in psychological health, potentially serving as an alternative choice for
interventions. This comprehensive review analyses 28 publications, among which three are in English and 25 in Chinese, these indicating enhancement
in quality of life and mental health for a variety of participants, including college students, middle-aged individuals, the elderly, and patients
who suffer from different mental problems or chronic physical illnesses. The outcomes suggest that this cost-effective, learner-friendly and self-
pacing exercise should be promoted in individual and group settings for both curative and preventive measures, and for which further investigations
are also recommended.
Journal of Bodywork & Movement Therapies, 19(1) : 138-
149
- Year: 2015
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Mind-body exercises (e.g. yoga, tai chi, qigong)
Bellon, J. A., Moreno-Peral, P., Motrico,
E., RodrIguez-Morejon, A., Fernandez, A., Serrano-Blanco, A., Zabaleta-del-Olmo,
E., Conejo-Ceron, S.
Objective: To determine the effectiveness of psychological and/or educational
interventions to prevent the onset of episodes of depression.; Methods: Systematic review of systematic reviews and meta-analyses (SR/MA). We
searched PubMed, PsycINFO, Cochrane Database of Systematic Reviews, OpenGrey, and PROSPERO from their inception until February 2014. Two reviewers
independently evaluated the eligibility criteria of all SR/MA, abstracted data, and determined bias risk (AMSTAR).; Results: Twelve SR/MA (156 non-
repeated trials and 56,158 participants) were included. Of these, 142 (91%) were randomized-controlled, 13 (8.3%) controlled trials, and 1 (0.6%) had
no control group. Five SR/MA focused on children and adolescents, four on specific populations (women after childbirth, of low socioeconomic status,
or unfavorable circumstances; patients with severe traumatic physical injuries or stroke) and three addressed the general population. Nine (75%)
SR/MA concluded that interventions to prevent depression were effective. Of the 156 trials, 137 (87.8%) reported some kind of effect size
calculation. Effect sizes were small in 45 (32.8%), medium in 26 (19.1%), and large in 25 (18.2%) trials; 41 (29.9%) trials were not effective. Of
the 141 trials for which follow-up periods were available, only 34 (24.1%) exceeded 12 months.; Conclusion: Psychological and/or educational
interventions to prevent onset of episodes of depression were effective, although most had small or medium effect sizes.; Copyright © 2014. Published
by Elsevier Inc.
Preventive Medicine, 76 Suppl : S22-
S32
- Year: 2015
- Problem: Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Psychoeducation
Chu, I.
H., Lin, Y. J., Wu, W. L., Chang, Y. K., Lin, I. M.
Objective: To examine
the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women. Design: Randomized controlled trial.
Participants: Fifty-two healthy women were randomly assigned to a yoga group or a control group. Interventions: Participants in the yoga group
completed an 8-week yoga program, which comprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose
practice, and supine meditation/relaxation. The control group was instructed not to engage in any yoga practice and to maintain their usual level of
physical activity during the study. Outcome measures: Participants' heart rate variability, perceived stress, depressive symptoms, and state and
trait anxiety were assessed at baseline (week 0) and after the intervention (week 9). Results: No measures of heart rate variability changed
significantly in either the yoga or control group after intervention. State anxiety was reduced significantly in the yoga group but not in the
control group. No significant changes were noted in perceived stress, depression, or trait anxiety in either group. Conclusions: An 8-week yoga
program was not sufficient to improve heart rate variability. However, such a program appears to be effective in reducing state anxiety in generally
healthy women. Future research should involve longer periods of yoga training, include heart rate variability measures both at rest and during yoga
practice, and enroll women with higher levels of stress and trait anxiety.
Journal of Alternative & Complementary Medicine, 21(12) : 789-795
- Year: 2015
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Mind-body exercises (e.g. yoga, tai chi, qigong)
Cicchetti, D., Toth, S.
L., Handley, E. D.
Genetic moderation of interpersonal psychotherapy (IPT) efficacy for economically
disadvantaged women with major depressive disorder was examined. Specifically, we investigated whether genotypic variation in corticotropin releasing
hormone receptor 1 (CRHR1) and the linked polymorphic region of the serotonin transporter gene (5-HTTLPR) moderated effects of IPT on depressive
symptoms over time. We also tested genotype moderation of IPT mechanisms on social adjustment and perceived stress. Non-treatment-seeking urban women
at or below the poverty level with infants were recruited from the community (N = 126; M age = 25.33 years, SD = 4.99; 54.0% African American, 22.2%
Caucasian, and 23.8% Hispanic/biracial) and randomized to individual IPT or Enhanced Community Standard groups. The results revealed that changes in
depressive symptoms over time depended on both intervention group and genotypes (5-HTTLPR and CRHR1). Moreover, multiple-group path analysis
indicated that IPT improved depressive symptoms, increased social adjustment, and decreased perceived stress at posttreatment among women with the 0
copies of the CRHR1 TAT haplotype only. Finally, improved social adjustment at postintervention significantly mediated the effect of IPT on reduced
depressive symptoms at 8 months postintervention for women with 0 copies of the TAT haplotype only. Post hoc analyses of 5-HTTLPR were indicative of
differential susceptibility, albeit among African American women (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
Development & Psychopathology, 27(1) : 19-35
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Interpersonal therapy (IPT)
Chien, W-T., Bressington, D.
This study aimed to test the
effectiveness of a nurse-led structured psychosocial intervention program in Chinese patients with first-onset mental illness. A single-blind,
parallel group, randomized controlled trial design was used. The study involved 180 participants with mild to moderate-severe symptoms of psychotic
or mood disorders who were newly referred to two psychiatric outpatient clinics in Hong Kong. Patients were randomly assigned to either an eight-
session nurse-led psychosocial intervention program (plus usual care) or usual psychiatric outpatient care (both n=90). The primary outcome was
psychiatric symptoms. Outcomes were measured at recruitment, one week and 12 months post-intervention. Patients in the psychosocial intervention
group reported statistically significant improvements in symptoms compared to treatment as usual. There were also significant improvements in illness
insight and perceived quality of life and reduction in length of re-hospitalizations over the 12-month follow-up. The findings provide evidence that
the nurse-led psychosocial intervention program resulted in improved health outcomes in Chinese patients with first-onset mental illness.; Copyright
© 2015 Elsevier Ireland Ltd. All rights reserved.
Psychiatry Research, 229(1-2) : 277-
286
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Psychoeducation, Skills training, Other service delivery and improvement
interventions
Chen, C-
J., Sung, H-C., Lee, M-S, Chang, C-Y.
This study aimed to evaluate the effects of Chinese five-element music therapy on nursing students with depressed mood. We
randomly assigned 71 nursing students from Taiwan with depressed mood to the music and control groups. The music group (n = 31) received Chinese
five-element music therapy, whereas the participants in the control group (n = 40) maintained their routine lifestyles with no music therapy. All of
the participants were assessed using the Depression Mood Self-Report Inventory for Adolescence, and their salivary cortisol levels were measured. The
study found that there was a significant reduction in depression between the pre- and posttherapy test scores and in salivary cortisol levels over
time in the music group. After receiving the music therapy, the nursing students' depression levels were significantly reduced (P = 0.038) compared
with the control group (P < 0.001). These results indicate that the Chinese five-element music therapy has the potential to reduce the level of
depression in nursing students with depressed mood. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
International Journal of
Nursing Practice, 21(2) : 192-199
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Creative expression: music, dance, drama, art
Cecchini-Estrada, J-A., Mendez-Gimenez, A., Cecchini, C., Moulton, M., Rodriguez, C.
This study was designed with a dual goal: (1) to compare the
change in the scores of depressive symptoms by means of the implementation of three intervention programs in comparison to a control group: a) based
on Epstein's TARGET (ET), b) without TARGET strategies (NET), and c) under conditions of active exercise (AE); and (2) to analyze whether the Self-
determination Index (SDI) predicts the reduction of depressive symptoms. The participants (N = 106; 68 females and 38 males), aged between 18-30
years, were randomly assigned to one of the groups. Each treatment lasted 8 weeks (3 hours/week). Of the ET participants, 59.26% showed a therapeutic
response, defined as a 50% reduction in the reference score, versus 25.93% for the NET, 19.23% for the AE, and 3.84% for the control group. After six
months, the ET group increased their percentage of therapeutic response by slightly more than 10%, which did not occur in the other groups. SDI
predicted lower levels of depressive symptoms, and our findings indicate that TARGET strategies can have a direct effect on depressive symptoms at
the time of intervention and an indirect effect at a later stage due to their impact on future levels of physical activity. (PsycINFO Database Record
(c) 2016 APA, all rights reserved) (journal abstract).
International Journal of Clinical & Health Psychology, 15(3) : 191-
199
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Physical activity, exercise
Brent, D. A., Brunwasser, S. M., Hollon, S. D., Weersing, V., Clarke, G. N., Dickerson, J. F., Beardslee, W. R., Gladstone, T. R., Porta, G., Lynch, F. L., Iyengar, S., Garber, J.
IMPORTANCE Adolescents whose parents have a history of depression are at risk for
developing depression and functional impairment. The long-term effects of prevention programs on adolescent depression and functioning are not known.
OBJECTIVE To determine whether a cognitive-behavioral prevention (CBP) program reduced the incidence of depressive episodes, increased depression-
free days, and improved developmental competence 6 years after implementation. DESIGN, SETTING, AND PARTICIPANTS A 4-site randomized clinical trial
compared the effect of CBP plus usual care vs usual care, through follow-up 75 months after the intervention (88% retention), with recruitment from
August 2003 through February 2006 at a health maintenance organization, university medical centers, and a community mental health center. A total of
316 participants were 13 to 17 years of age at enrollment and had at least 1 parent with current or prior depressive episodes. Participants could not
be in a current depressive episode but had to have subsyndromal depressive symptoms or a prior depressive episode currently in remission. Analysis
was conducted between August 2014 and June 2015. INTERVENTIONS The CBP program consisted of 8 weekly 90-minute group sessions followed by 6 monthly
continuation sessions. Usual care consisted of any family-initiated mental health treatment. MAIN OUTCOMES AND MEASURES The Depression Symptoms
Rating scale was used to assess the primary outcome, new onsets of depressive episodes, and to calculate depression-free days. A modified Status
Questionnaire assessed developmental competence (eg, academic or interpersonal) in young adulthood. RESULTS Over the 75-month follow-up, youths
assigned to CBP had a lower incidence of depression, adjusting for current parental depression at enrollment, site, and all interactions (hazard
ratio, 0.71 [95%CI, 0.53-0.96]). The CBP program's overall significant effect was driven by a lower incidence of depressive episodes during the
first 9 months after enrollment. The CBP program's benefit was seen in youths whose index parent was not depressed at enrollment, on depression
incidence (hazard ratio, 0.54 [95% CI, 0.36-0.81]), these effects on developmental competence were mediated via the CBP program's effect on
depression-free days. CONCLUSIONS AND RELEVANCE The effect of CBP on new onsets of depression was strongest early and was maintained throughout the
follow-up period; developmental competence was positively affected 6 years later. The effectiveness of CBP may be enhanced by additional booster
sessions and concomitant treatment of parental depression. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
JAMA Psychiatry, 72(11) : 1110-1118
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Cognitive & behavioural therapies (CBT)
Buttigieg, J. P., Shortt, A. L., Slaviero, T. M., Hutchinson, D., Kremer, P., Toumbourou, J. W.
This study aimed to evaluate whether an intervention prevented the development of depressive
symptoms through the early years of secondary school (Grades 7 to 9-mean ages 12.3 to 14.5 years) in Victoria, Australia. Twelve schools were
randomized to a universal preventative intervention (including a student social relationship/emotional health curriculum, and parent/caregiver
parenting education); 12 were randomized as control schools. Multivariate regression analyses used student self-report to predict depressive symptoms
at 26-month follow-up (13-months after intervention completion) from baseline measures and intervention status (N = 2027). There was no overall
intervention effect on depressive symptoms. However, intervention students with moderate symptoms whose parents attended parent education events had
a significantly reduced risk of depressive symptoms at follow-up. Future evaluations of interventions of this type should investigate: therapeutic
processes; methods to increase recruitment into effective parent education events; and the potential to target assistance to students with high
depressive symptoms. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
Journal of
Adolescence, 44 : 204-213
- Year: 2015
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions