Disorders - Depressive Disorders
Hunt, X., Shakespeare,
T., Vilyte, G., Melendez-Torres, G. J., Henry, J., Bradshaw, M., Naidoo, S., Mbuyamba, R., Aljassem, S., Suubi, E., Aljasem, N., Makhetha, M., Bantjes, J.
Background: Adolescents who are socially excluded are at increased risk of mental health problems such as
depression and anxiety. Promoting social inclusion could be an effective strategy for preventing and treating adolescent depression and anxiety.
Method(s): We conducted a systematic review of intervention studies which aimed to prevent or treat adolescent depression and/or anxiety by promoting
social inclusion. Throughout the review we engaged a youth advisory group of 13 young people (aged 21-24) from Uganda, Turkey, Syria, South Africa,
and Egypt. Result(s): We identified 12 studies relevant to our review. The interventions tested use a range of different strategies to increase
social inclusion and reduce depression and anxiety, including social skills training, psychoeducation, teaching life skills training, and cash
transfers. Pooled standardised mean differences (SMDs) based on random-effects models showed medium-to-large benefits of interventions on improving
depression and anxiety symptoms (n = 8; SMD = -0.62; 95% CI, -1.23 to -0.01, p < 0.05). Conclusion(s): Although there are not many studies, those
which have been done show promising results that strongly suggest that social inclusion could be an important component of programmes to promote
adolescent mental health. Copyright © 2023 by the authors.
International Journal of Environmental Research and Public
Health, 20(3) :
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Hospital, M. M., Clarke, R. D., Morris, S. L., Fernandez, S. B., Spadola, C. E., Wagner, E. F.
Latinx youth with mental health disorders have worse outcomes when compared to their White (non-Hispanic) counterparts.
Latinx youth also have less access to and lower utilization of mental health services. Emerging research supports the psychological and physical
benefits of engaging in yoga and yoga may function as a complimentary treatment option for patients with mental health challenges. However, research
assessing the efficacy of yoga and mindfulness is particularly sparse among Latinx youth, who may particularly benefit from mind body awareness
activities given barriers to more traditional health approaches. The objective of this quasi-experimental study was to examine the effects of a 12-
week Vinyasa flow-based yoga group intervention on anxiety, depression, empathy, and life satisfaction among adolescents receiving outpatient mental
health treatment. Adolescents (n = 186; 12-17 years old) were recruited to an active intervention condition (Yoga); a subsequent group of
participants (n = 91) were recruited in the same manner to an assessment-only comparison control condition (Comparison). The Yoga group participated
in culturally and developmentally tailored group yoga classes for 12 weeks. Structural equation modelling was used to evaluate the main effect
intervention response between participants in the two conditions. At the post-intervention assessment, after controlling for baseline levels of
outcome variables (i.e., depression, anxiety, empathy, and life satisfaction), on average participants in the yoga condition reported: less
depression symptoms (B = -1.54, p = 0.008), less anxiety symptoms (B = -0.75, p = 0.048), greater empathy (B = 1.32, p = 0.025) and greater life
satisfaction (B = 0.30, p = 0.013) as compared to the Comparison condition. Yoga interventions can be an acceptable and feasible modality for
promoting well-being and reducing mental health problems among Latinx youth. Copyright © 2022 John Wiley & Sons Ltd.
Stress and Health, 39(3) : 516-
524
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Controlled clinical trials
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Mind-body exercises (e.g. yoga, tai chi, qigong), Physical activity, exercise
Hohne, E., Boge, K., Karnouk, C., Tschorn, M., Banaschewski, T., Hoell, A., Sukale, T., Plener, P., Schneider, F., Padberg, F., Hasan, A., Rapp, M. A., Bajbouj,
M., Kamp-Becker, I.
Adolescent refugees and asylum seekers (ARAS) are highly vulnerable to mental health problems. Stepped care
models (SCM) and culturally sensitive therapies offer promising treatment approaches to effectively provide necessary medical and psychological
support. To our knowledge, we were the first to investigate whether a culturally sensitive SCM will reduce symptoms of depression and PTSD in ARAS
more effectively and efficiently than treatment as usual (TAU). We conducted a multicentric, randomized, controlled and rater-blinded trial across
Germany with ARAS between the ages of 14 to 21 years. Participants (N = 158) were stratified by their level of depressive symptom severity and then
equally randomized to either SCM or TAU. Depending on their severity level, SCM participants were allocated to tailored interventions. Symptom
changes were assessed for depression (PHQ) and PTSD (CATS) at four time points, with the primary end point at post-intervention after 12 weeks. Based
on an intention-to-treat sample, we used a linear mixed model approach for the main statistical analyses. Further evaluations included cost-utility
analyses, sensitivity analyses, follow-up-analyses, response and remission rates and subgroup analysis. We found a significant reduction of PHQ (d =
0.52) and CATS (d = 0.27) scores in both groups. However, there was no significant difference between SCM and TAU. Cost-utility analyses indicated
that SCM generated greater cost-utility when measured as quality-adjusted life years compared to TAU. Subgroup analysis revealed different effects
for the SCM interventions depending on the outcome measure. Although culturally sensitive, SCMs did not prove to be more effective in symptom change
and represent a more cost-effective treatment alternative for mentally burdened ARAS. Our research contributes to the optimization of clinical
productivity and the improvement of therapeutic care for ARAS. Disorder-specific interventions should be further investigated. Copyright © 2023, The
Author(s).
European Child and Adolescent Psychiatry., :
- Year: 2023
- Problem: Post Traumatic Stress Disorder, Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Dialectical behavioural therapy
(DBT), Psychoeducation, Other Psychological Interventions, Trauma-focused cognitive behavioural therapy (TF-
CBT), Technology, interventions delivered using technology (e.g. online, SMS)
Hilt, L. M., Swords, C. M., Webb, C. A.
OBJECTIVE: Rumination is a risk factor for the development of internalizing psychopathology that often emerges during adolescence.
The goal of the present study was to test a mindfulness mobile app intervention designed to reduce rumination. METHOD(S): Ruminative adolescents
(N=152; 59% girls, 18% racial/ethnic minority, Mage=13.72, SD=.89) were randomly assigned to use a mobile app 3 times per day for 3weeks that
delivered brief mindfulness exercises or a mood monitoring-only control. Participants reported on rumination, depressive symptoms and anxiety
symptoms at baseline, post-intervention and at 3 follow-up timepoints: 6weeks, 12weeks, and 6months post-intervention. Parents reported on
internalizing symptoms. RESULT(S): There was a significant Time X Condition effect at post-intervention for rumination, depressive symptoms, and
anxiety symptoms, such that participants in the mindfulness intervention showed improvements relative to those in the control condition. The effect
for rumination lasted through the 6-week follow-up period; however, group differences were generally not observed throughout the follow-up period,
which may indicate that continued practice is needed for gains to be maintained. CONCLUSION(S): This intervention may have the potential to prevent
the development of psychopathology and should be tested in a longitudinal study assessing affective disorder onset, especially in populations with
limited access to conventional, in person mental health care.This study was registered with Clinicaltrials.gov (Identifier NCT03900416).
Journal of
Clinical Child & Adolescent Psychology, : 1-14
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Mindfulness based
therapy, Technology, interventions delivered using technology (e.g. online, SMS)
Hechanova, M. R. M., Jocson, R. M., Alianan, A. S., Delos Santos,
J. J. I., Manaois, J. O., Gomez, G. A., Lamzon, G. R.
This study evaluated two forms of a resilience intervention amongst college students during the COVID-19
pandemic. Utilising a randomised controlled trial design, it examined the impact of a synchronous and asynchronous resilience interventions versus a
control group that did a journaling intervention. Outcomes measured included coping behaviour, non-reactivity, wellbeing, stress, depression and
anxiety. Participants consisted of Filipino college students randomly assigned to three groups: synchronous online resilience group (n = 135),
asynchronous resilience group (n = 121) and control group (n = 127). Results revealed that students who went through the online synchronous
resilience reported a significant reduction in depression at post-intervention compared to those who went through an asynchronous intervention.
Post-intervention scores for nonreactivity were also higher in the synchronous group compared to both asynchronous and journaling groups. Effect
sizes were small to moderate. This study suggests that online resilience interventions are viable means to address the mental health needs of
students, especially in countries with limited mental health resources. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
Research in Learning Technology, 31 : ArtID
2890
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other Psychological Interventions, Other service delivery and improvement
interventions
He, Y., Li, Z., Cao, L., Han, M., Tu,
J., Deng, H., Huang, Z., Geng, X., Wu, J.
Individuals with high-level perceived stress are at higher risk of developing a psychiatric disorder. While repetitive transcranial
magnetic stimulation (rTMS) is effective for improving emotional symptoms, there is little evidence of its effect on perceived stress. This
randomized sham-controlled trial investigated the effect of rTMS on ameliorating high-level stress and explored the associated changes in brain
network activity. Fifty participants with high-level perceived stress were randomly assigned to either the active or sham rTMS group and received 12
active/sham rTMS sessions over four weeks (three per week). Perceived stress score (PSS), Chinese affective scale (CAS) normal and now statuses, and
functional network topology were measured. Our results showed greater improvements in PSS and CAS_Normal scores, and reduced path length in the
default mode network after active rTMS. Functional activations of the angular gyrus, posterior insula, and prefrontal cortex were also modulated in
the active group. There were significant associations between posterior insula efficiency and PSS scores, and between angular efficiency and CAS_Now
scores in the active group. These cumulative findings suggest rTMS as a promising intervention for recovery from high-level perceived stress.
Psychiatry
Research, 326 : 115297
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Biological Interventions
(any), Transcranial magnetic stimulation
(TMS)
Harra, R. C., Vargas, I.
Objective: The study evaluated the feasibility and acceptability, as well as
conducted an initial test of effectiveness, of a peer-based mentoring program for mental health problems among college students. Participant(s):
Thirty-two undergraduate students from a University in the southern part of the United States who exhibited moderate depression or anxiety symptoms
were assessed. The participants were primarily white and in their freshman year. Method(s): Participants were randomized into two groups.
Participants in the intervention group met with a trained peer mentor once a week for four weeks, while participants in the control group were placed
on a waitlist. All participants completed pre- and post-treatment surveys to assess anxiety and depression symptoms. Result(s): The data indicated
that participants in the intervention group had significantly greater post-treatment reductions in depression symptoms. Conclusion(s): These findings
provide preliminary support for the use of peer-based mentoring programs in treating mental health problems on college campuses.
, : 1-8
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Han, M., Zhang, Y., Wang,
Y., Ou, J., Ren, D., Cai, C., Liu, K., Li, R., Han, J., Chen, R.
Background AU LGBTQ+: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly community's higher susceptibility to worse mental:health
outcomes and more help-seeking barriers compared to the cis-heterosexual population. Despite the LGBTQ+ population facing higher mental health risks,
there has been a dearth of research focusing on developing tailored interventions targeting them. This study aimed to assess the effectiveness of a
digital multicomponent intervention in promoting help-seeking for mental health issues in LGBTQ+ young adults. Methods and findings We recruited
LGBTQ+ young adults aged between 18 and 29 who scored moderate or above on at least 1 dimension of the Depression Anxiety Stress Scale 21 and did not
have help-seeking experiences in the past 12 months. Participants (n = 144) were stratified by gender assigned at birth (male/female) and randomly
allocated (1:1 ratio) to the intervention or active control parallel condition by generating a random number table, so they were blinded to the
intervention condition. All participants received online psychoeducational videos, online facilitator-led group discussions, and electronic brochures
in December 2021 and January 2022, with the final follow-up in April 2022. The contents of the video, discussion, and brochure are help-seeking for
the intervention group and general mental health The current intervention was an effective approach in promoting help-seeking intentions, mental
health literacy, and help-seeking encouragement-related knowledge. Its brief yet integrated intervention format could also be utilized in treating
other imminent concerns confronted by LGBTQ+ young adults. Copyright © 2023 Public Library of Science. All rights reserved.
PLoS Medicine, 20(3) :
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Other Psychological Interventions, Technology, interventions delivered using technology (e.g. online, SMS)
Gunebakan, O., Acar, M.
Background and
aims: This study was planned to examine the effects of tele-yoga training on menstrual symptoms, quality of life, anxiety-depression level, body
awareness, and self-esteem in healthy women. Method(s): Thirty-two healthy premenopausal women between the ages of 18 and 45 were included in the
study. The women were randomly divided into two groups as tele-yoga training (n: 16) and the control group (n: 16). The tele-yoga training was
performed on the Zoom software for 6 weeks, 2 times a week and 45 min a day. No intervention was made in the control group. Menstrual pain and
symptoms by Menstrual Symptom Scale (MSS), quality of life by Nottingham Health Profile (NHP), depression levels by Beck Depression Scale (BDS),
anxiety levels by State and Trait Anxiety Scale (STAI), body awareness by Body Awareness Questionnaire (BAQ), and self-esteem by Rosenberg Self-
Esteem Scale (RSES) were determined. Result(s): In the tele-yoga training group, statistically significant improvements were observed in the MSS
total (p = 0.001), negative effects (p = 0.003), menstrual pain symptoms (p = 0.003), coping methods (p = 0.001) sub-parameters, BDS score (p =
0.000), NHP sleep (p = 0.021), energy (p = 0.002), emotional (p = 0.000), and isolation (p = 0.039) sub-parameters. In the control group, there was
statistically significant worsening in the NHP total score (p = 0.000). As regards the differences in values between the two groups, there were
statistically difference in favor of the training group in sub-parameters of MSS, NHP sleep, energy, emotional, and isolation sub-parameters, and BDS
and BAQ scores (p < 0.05). Conclusion(s): It is thought that tele-yoga training may be a safe and effective method in reducing menstrual symptoms and
depression, increasing quality of life, and body awareness. Copyright © 2022, The Author(s), under exclusive licence to Royal Academy of Medicine in
Ireland.
Irish Journal of Medical Science, 192
(1) : 467-479
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Randomised controlled trials
-
Stage: Universal prevention
-
Treatment and intervention: Complementary & Alternative
Interventions (CAM), Service Delivery & Improvement, Mind-body exercises (e.g. yoga, tai chi, qigong), Physical activity, exercise, Technology, interventions delivered using technology (e.g. online, SMS)
Gonsalves, P. P., Nair, R., Roy, M., Pal, S., Michelson,
D.
Self-disclosure, referring to the ability to communicate and share intimate personal feelings, has strong face validity
for many young people as a way of improving anxiety and depression outcomes. The current review aimed to generate the first comprehensive evidence
synthesis of self-disclosure interventions involving young people aged 14-24 years who are either disclosers or recipients of personal information
about living with anxiety and/or depression. A systematic review of quantitative and qualitative data was combined with new insights from an
adolescents and young adults lived-experience panel (n=7) with the intention to combine rigorous systematic review methods and experiential
knowledge. Six studies of variable quality were included in this review, five were quantitative and one was qualitative. Findings suggest that self-
disclosure may be effective at reducing symptoms for adolescents and young adults with established depression; effects were not apparent when
delivered as early prevention. No evidence for impacts on anxiety was found. The potential for negative effects like bullying or harassment was
identified. Findings were limited by a small number of studies; low representation of peer-reviewed studies from low-or middle-income countries; and
varied interventions in terms of format, participants' context, and nature of delivery. Self-disclosure may be of value in the context of
interventions intended explicitly to reduce depression for those already showing symptoms. Delivery by non-specialists (such as peers and teachers)
in addition to mental health professionals can help build capacity in community health systems. Self-disclosure may also be helpful at reducing
stigma and stimulating help-seeking at earlier stages of mental health problems. Copyright © 2023. The Author(s).
Administration and Policy in Mental Health, 50(3) : 488-
505
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention), Disorder established (diagnosed disorder)
-
Treatment and intervention: Psychological Interventions
(any), Other Psychological Interventions
Gong, X. G., Wang, L.
P., Rong, G., Zhang, D. N., Zhang, A. Y., Liu, C.
Objectives: Mental health problems among university students are a cause of widespread concern. Mindfulness-based interventions (MBIs)
delivered online have considerable potential to help university students manage mental health challenges. However, there is no consensus regarding
the efficacy of online MBIs. This meta-analysis aims to determine whether MBIs are feasible and effective for improving university students' mental
health.\rMethods: Randomised controlled trials (RCTs) in Web of Science, PubMed, Cochrane Library, Embase and the US National Library of Medicine
(Clinical Trial Registry) published through August 31, 2022, were searched. Two reviewers selected the trials, conducted a critical appraisal, and
extracted the data. Nine RCTs met our inclusion criteria.\rResults: This analysis showed that online MBIs were effective in improving depression
(standardised mean difference [SMD] = -0.27; 95% confidence interval [CI], -0.48 to -0.07; P = 0.008), anxiety (SMD = -0.47; 95% CI, -080 to -0.14; P
= 0.006), stress (SMD = -0.58; 95% CI, -0.79 to -0.37; P < 0.00001), and mindfulness (SMD = 0.71; 95% CI, 0.17 to 1.25; p = 0.009) in university
students. No significant effect was found on wellbeing (SMD = 0.30; 95% CI, -0.00 to 0.60; P = 0.05).\rConclusion: The findings indicated that online
MBIs could effectively improve the mental health of university students. Nevertheless, additional rigorously designed RCTs are required.\rSystematic
review registration: https://inplasy.com/inplasy-2022-9-0099/, identifier INPLASY202290099.
, 14 : 1073647
- Year: 2023
- Problem: Anxiety Disorders (any), Depressive Disorders
- Type: Systematic reviews
-
Stage: Universal prevention, At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Mindfulness based
therapy, Technology, interventions delivered using technology (e.g. online, SMS)
Ghosh, A., Cherian, R. J., Wagle, S., Sharma, P., Kannan, K. R., Bajpai, A., Gupta, N.
BACKGROUND: Globally, most individuals
who are susceptible to depression do not receive adequate or timely treatment. Unguided computerized cognitive behavioral therapy (cCBT) has the
potential to bridge this treatment gap. However, the real-world effectiveness of unguided cCBT interventions, particularly in low- and middle-income
countries (LMICs), remains inconclusive.\rOBJECTIVE: In this study, we aimed to report the design and development of a new unguided cCBT-based
multicomponent intervention, TreadWill, and its pragmatic evaluation. TreadWill was designed to be fully automated, engaging, easy to use, and
accessible to LMICs.\rMETHODS: To evaluate the effectiveness of TreadWill and the engagement level, we performed a double-blind, fully remote, and
randomized controlled trial with 598 participants in India and analyzed the data using a completer's analysis.\rRESULTS: The users who completed at
least half of the modules in TreadWill showed significant reduction in depression-related (P=.04) and anxiety-related (P=.02) symptoms compared with
the waitlist control. Compared with a plain-text version with the same therapeutic content, the full-featured version of TreadWill showed
significantly higher engagement (P=.01).\rCONCLUSIONS: Our study provides a new resource and evidence for the use of unguided cCBT as a scalable
intervention in LMICs.\rTRIAL REGISTRATION: ClinicalTrials.gov NCT03445598; https://clinicaltrials.gov/ct2/show/NCT03445598.
Journal of Medical Internet
Research, 25 : e41005
- Year: 2023
- Problem: Depressive Disorders
- Type: Randomised controlled trials
-
Stage: At risk (indicated or selected prevention)
-
Treatment and intervention: Service Delivery & Improvement, Psychological Interventions
(any), Cognitive & behavioural therapies (CBT), Technology, interventions delivered using technology (e.g. online, SMS)